DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and Zfp369

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_848141.3	Gene:	Zfp369 / 170936	MGIID:	2176229	Length:	845	Species:	Mus musculus

Alignment Length:	187	Identity:	59/187 - (31%)
Similarity:	89/187 - (47%)	Gaps:	24/187 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 KNDDTDFLKPAKKKRKTYISQ--------KVH------ICDHCGKKFTDKGNFNLHVLRHSGVKP 307
            :..|...|:.|...||. ||:        |:|      .|..|||.|.:...|::|...|:|.:|
Mouse   665 RGSDVGRLRRANNCRKA-ISRHAQQISFIKIHKGSQICQCSECGKMFRNARYFSVHKKIHTGERP 728

  Fly   308 FECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCN 372
            :.|..||:.......|..|:|: |.||:|:.|..|...|...:..|:| .|.|...|.   ::|.
Mouse   729 YMCMSCGKAFVQSSSLTQHLRI-HSGERPFECSECGRTFSDRSAASQH-LRTHTGAKP---YQCQ 788

  Fly   373 YCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNL----KTHYRSRQHQNKL 425
            :|.|.:..:....:|..:|||||.:.|..|..:||::|||    |||.:..:.|.||
Mouse   789 HCGKAFRQSSHLTRHVRIHTGERPYVCTKCGKAFTQSSNLIGHQKTHRKKFKKQPKL 845

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	6/20 (30%)
		C2H2 Zn finger	339..360	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	10/26 (38%)
		C2H2 Zn finger	399..417	CDD:275368	10/21 (48%)
Zfp369	NP_848141.3	KRAB	35..94	CDD:214630
		KRAB	35..74	CDD:279668
		SCAN	179..266	CDD:280241
		KRAB	300..>340	CDD:214630
		KRAB	300..339	CDD:279668
		C2H2 Zn finger	676..695	CDD:275370	5/19 (26%)
		C2H2 Zn finger	703..723	CDD:275368	7/19 (37%)
		zf-H2C2_2	715..740	CDD:290200	8/24 (33%)
		COG5048	727..>792	CDD:227381	21/69 (30%)
		C2H2 Zn finger	731..751	CDD:275368	6/20 (30%)
		zf-H2C2_2	743..767	CDD:290200	9/24 (38%)
		zf-C2H2	757..779	CDD:278523	6/22 (27%)
		C2H2 Zn finger	759..779	CDD:275368	6/20 (30%)
		zf-C2H2	785..807	CDD:278523	4/21 (19%)
		C2H2 Zn finger	787..807	CDD:275368	4/19 (21%)
		zf-H2C2_2	799..824	CDD:290200	9/24 (38%)
		C2H2 Zn finger	815..835	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000