DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17802 and ZNF483

DIOPT Version :9

Sequence 1:NP_650659.2 Gene:CG17802 / 42143 FlyBaseID:FBgn0038549 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_597721.2 Gene:ZNF483 / 158399 HGNCID:23384 Length:744 Species:Homo sapiens


Alignment Length:391 Identity:88/391 - (22%)
Similarity:153/391 - (39%) Gaps:116/391 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 EEDHDLYKK-----EEEESEVNENKEFEDIACEIPFS---------KEDDEQEQQQEYEDMVDKK 174
            :|..||.|.     .::....||:|:        |||         ||....|:.::..| ..|.
Human   312 KETSDLIKHLRVYLRKKSRRYNESKK--------PFSFHSDLVLNRKEKTAGEKSRKSND-GGKV 367

  Fly   175 TGHDD-------------GEESQE---------------------CEESQPDE-EESQQNEEDEE 204
            ..|..             |:.||:                     ||:.:.|. :|:..|:::..
Human   368 LSHSSALTEHQKRQKIHLGDRSQKCSKCGIIFIRRSTLSRRKTPMCEKCRKDSCQEAALNKDEGN 432

  Fly   205 ESQEDDDELWQ--------------------------NEDGDSDTDADSMSDIEATS-------- 235
            ||.|...:..:                          ||.|.:.:|:.|::....|.        
Human   433 ESGEKTHKCSKCGKAFGYSASLTKHRRIHTGEKPYMCNECGKAFSDSSSLTPHHRTHSGEKPFKC 497

  Fly   236 --------------RQSALDEDKKPRRKYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCG 286
                          :...:...:|| .|......|.:|.:..:    :.::.:..:|.:.|.:||
Human   498 DDCGKGFTLSAHLIKHQRIHTGEKP-YKCKDCGRPFSDSSSLI----QHQRIHTGEKPYTCSNCG 557

  Fly   287 KKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTM 351
            |.|:...:.:.|...|:|.||::|.|||:.......|..|.|: |.|||||.|..|...|.|.|.
Human   558 KSFSHSSSLSKHQRIHTGEKPYKCGECGKAFRQNSCLTRHQRI-HTGEKPYLCNDCGMTFSHFTS 621

  Fly   352 RSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHY 416
            ...|: |:|..:|.   :|||.|:|.:.::...::|:.:|||.:.:.|:.|..||:::|:|..|:
Human   622 VIYHQ-RLHSGEKP---YKCNQCEKAFPTHSLLSRHQRIHTGVKPYKCKECGKSFSQSSSLNEHH 682

  Fly   417 R 417
            |
Human   683 R 683

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17802NP_650659.2 zf-AD 4..74 CDD:285071
C2H2 Zn finger 282..302 CDD:275368 6/19 (32%)
C2H2 Zn finger 310..331 CDD:275368 7/20 (35%)
C2H2 Zn finger 339..360 CDD:275368 7/20 (35%)
C2H2 Zn finger 371..388 CDD:275370 4/16 (25%)
zf-met 398..421 CDD:289631 8/20 (40%)
C2H2 Zn finger 399..417 CDD:275368 7/17 (41%)
ZNF483NP_597721.2 SCAN 49..152 CDD:128708
SCAN 49..136 CDD:280241
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 137..156
KRAB 171..229 CDD:214630
KRAB 171..209 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 263..308
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..385 6/35 (17%)
C2H2 Zn finger 361..384 CDD:275368 3/23 (13%)
C2H2 Zn finger 413..433 CDD:275368 5/19 (26%)
COG5048 437..>735 CDD:227381 61/257 (24%)
C2H2 Zn finger 441..461 CDD:275368 0/19 (0%)
zf-H2C2_2 453..477 CDD:290200 3/23 (13%)
C2H2 Zn finger 469..489 CDD:275368 5/19 (26%)
zf-H2C2_2 485..505 CDD:290200 1/19 (5%)
C2H2 Zn finger 497..517 CDD:275368 0/19 (0%)
zf-H2C2_2 509..533 CDD:290200 4/24 (17%)
zf-C2H2 523..545 CDD:278523 3/25 (12%)
C2H2 Zn finger 525..545 CDD:275368 2/23 (9%)
zf-C2H2 579..601 CDD:278523 7/22 (32%)
C2H2 Zn finger 581..601 CDD:275368 7/20 (35%)
zf-H2C2_2 594..618 CDD:290200 12/24 (50%)
C2H2 Zn finger 609..629 CDD:275368 7/20 (35%)
zf-H2C2_2 625..644 CDD:290200 9/22 (41%)
C2H2 Zn finger 637..657 CDD:275368 5/19 (26%)
zf-H2C2_2 650..674 CDD:290200 8/23 (35%)
C2H2 Zn finger 665..685 CDD:275368 8/19 (42%)
zf-H2C2_2 677..702 CDD:290200 3/7 (43%)
C2H2 Zn finger 693..713 CDD:275368
zf-H2C2_2 706..730 CDD:290200
C2H2 Zn finger 721..741 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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