DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZFP92

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001129745.1	Gene:	ZFP92 / 139735	HGNCID:	12865	Length:	416	Species:	Homo sapiens

Alignment Length:	146	Identity:	56/146 - (38%)
Similarity:	83/146 - (56%)	Gaps:	7/146 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 SQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNR-YILNIHIRVKHRGEKPYAC 339
            ::|.::|..|||.|:...|...|.:.|||.||:.||||| |.|.| :.|..|.|: |.|||||||
Human   148 AEKRYLCQQCGKAFSRSSNLIKHRIIHSGEKPYACPECG-KLFRRSFALLEHQRI-HSGEKPYAC 210

  Fly   340 QFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKV 404
            ..|.:.|..|:...:|: .:|..::.   |.|..|.|.:..::...:|..||:|||.:.|..|..
Human   211 PECSKTFTRSSNLIKHQ-VIHSGERP---FACGDCGKLFRRSFALLEHARVHSGERPYACPECGK 271

  Fly   405 SFTRNSNLKTHYRSRQ 420
            :|:|:|||..|.|:.:
Human   272 AFSRSSNLIEHQRTHR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	11/21 (52%)
		C2H2 Zn finger	339..360	CDD:275368	5/20 (25%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	9/23 (39%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
ZFP92	NP_001129745.1	KRAB	14..74	CDD:214630
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	86..125
		COG5048	<145..286	CDD:227381	56/143 (39%)
		C2H2 Zn finger	154..174	CDD:275368	7/19 (37%)
		C2H2 Zn finger	182..202	CDD:275368	11/21 (52%)
		C2H2 Zn finger	210..230	CDD:275368	5/20 (25%)
		C2H2 Zn finger	238..258	CDD:275368	4/19 (21%)
		COG5048	262..>315	CDD:227381	10/26 (38%)
		C2H2 Zn finger	266..286	CDD:275368	9/19 (47%)
		C2H2 Zn finger	294..314	CDD:275368
		C2H2 Zn finger	322..342	CDD:275368
		zf-H2C2_2	335..359	CDD:404364
		C2H2 Zn finger	350..370	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	368..416
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960