DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17802 and ZNF641

DIOPT Version :9

Sequence 1:NP_650659.2 Gene:CG17802 / 42143 FlyBaseID:FBgn0038549 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_689533.2 Gene:ZNF641 / 121274 HGNCID:31834 Length:438 Species:Homo sapiens


Alignment Length:312 Identity:72/312 - (23%)
Similarity:109/312 - (34%) Gaps:99/312 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 DMVDKKTGHDDGEES-----QECEE---------SQPDEEESQQNEEDEE-----ESQEDDDELW 214
            ||:.:..|   |||.     |:.||         ....|.|....|.:.|     .|..:|..||
Human   157 DMLSQLEG---GEEQWVPDPQDLEERDILRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLW 218

  Fly   215 QNEDGDSDTDA-----------------DSMSDIEATSRQSALDEDKKPRRKYTKRSSPKNDDTD 262
             |.:.|...|:                 ||.|::..::...:|                      
Human   219 -NPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSL---------------------- 260

  Fly   263 FLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHI 327
             |:|             |.|..|||:|....:...|...|:|.:|:.|.:| :|.|.|....|..
Human   261 -LRP-------------HTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKC-EKTFGRRHHLIRH 310

  Fly   328 RVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKT---------------------PKNFKC 371
            :..|..:|...|..|.:.|..::..:.|: |||...|:                     ||...|
Human   311 QKTHLHDKTSRCSECGKNFRCNSHLASHQ-RVHAEGKSCKGQEVGESPGTRKRQRAPPVPKCHVC 374

  Fly   372 NYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQN 423
            ..|.|.:...:...:|.:.||||:.|.|..|:.||.|..:|..|..:.|.|:
Human   375 TECGKSFGRRHHLVRHWLTHTGEKPFQCPRCEKSFGRKHHLDRHLLTHQGQS 426

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17802NP_650659.2 zf-AD 4..74 CDD:285071
C2H2 Zn finger 282..302 CDD:275368 6/19 (32%)
C2H2 Zn finger 310..331 CDD:275368 6/20 (30%)
C2H2 Zn finger 339..360 CDD:275368 5/20 (25%)
C2H2 Zn finger 371..388 CDD:275370 3/16 (19%)
zf-met 398..421 CDD:289631 7/22 (32%)
C2H2 Zn finger 399..417 CDD:275368 7/17 (41%)
ZNF641NP_689533.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53
KRAB 109..170 CDD:214630 6/15 (40%)
KRAB 109..149 CDD:279668
Transactivation 171..265 20/130 (15%)
COG5048 227..>372 CDD:227381 35/182 (19%)
C2H2 Zn finger 266..286 CDD:275368 6/19 (32%)
zf-H2C2_2 278..303 CDD:290200 8/25 (32%)
C2H2 Zn finger 294..314 CDD:275368 6/20 (30%)
C2H2 Zn finger 322..342 CDD:275368 5/20 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 345..367 1/21 (5%)
COG5048 351..>430 CDD:227381 20/76 (26%)
zf-C2H2 372..394 CDD:278523 4/21 (19%)
C2H2 Zn finger 374..394 CDD:275368 4/19 (21%)
zf-H2C2_2 386..411 CDD:290200 10/24 (42%)
C2H2 Zn finger 402..422 CDD:275368 7/19 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 418..438 3/9 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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