DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and Zfp518b

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001074613.2	Gene:	Zfp518b / 100515	MGIID:	2140750	Length:	1082	Species:	Mus musculus

Alignment Length:	243	Identity:	54/243 - (22%)
Similarity:	88/243 - (36%)	Gaps:	53/243 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 QQQEYEDMVDK--KTGHDDGEESQECEESQPDEEESQQNEEDEEESQEDDDELWQNEDGDSDTDA 225
            |.:|.:|:.::  .|..:.|..|......||       |.....|.||....|:|.    |:.:|
Mouse     2 QIREMKDIGEQLYTTQVNGGPSSLTMSPKQP-------NRATRTERQEAQTLLYQG----SEAEA 55

  Fly   226 DSMS-----DIEATSRQSALDEDKKPRR--------KYTKRSSP---------------KNDDTD 262
            .:|:     ..::..:....|..|.|.:        |.:.|:.|               :|:...
Mouse    56 ATMTIATCVQCKSVHKIPTQDLRKGPGQSQDTYVCFKCSLRAVPTQLHFVNNNAGAAHVRNETET 120

  Fly   263 FLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECG-----QKEFNRYI 322
            ...|..|.:........:.||.|.....|...:..|.|:|..:: |.|..|.     :.||.|::
Mouse   121 ISSPVNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQHEEIR-FICSHCSYISYTKGEFQRHL 184

  Fly   323 LNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFK 370
                  |||.|..||.|::||...:.:....:|..|||......:.||
Mouse   185 ------VKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHERAGAKRPFK 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	6/25 (24%)
		C2H2 Zn finger	339..360	CDD:275368	5/20 (25%)
		C2H2 Zn finger	371..388	CDD:275370	54/243 (22%)
		zf-met	398..421	CDD:289631
		C2H2 Zn finger	399..417	CDD:275368
Zfp518b	NP_001074613.2	C2H2 Zn finger	140..160	CDD:275368	6/19 (32%)
		zf-H2C2_5	167..189	CDD:372805	8/27 (30%)
		C2H2 Zn finger	167..187	CDD:275368	6/25 (24%)
		C2H2 Zn finger	195..216	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8154
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950