DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and ZSCAN16

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001307484.1	Gene:	ZSCAN16 / 80345	HGNCID:	20813	Length:	348	Species:	Homo sapiens

Alignment Length:	374	Identity:	87/374 - (23%)
Similarity:	152/374 - (40%)	Gaps:	81/374 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EHAKSLFDKEA---RDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFRERCIRTNSSWF 74
            :|.:.|..::|   |:.|:.:.:|...|||  |...|:..:..||.|...::...:.::   :|.
Human    42 QHFRKLCYQDAPGPREALTQLWELCRQWLR--PECHTKEQILDLLVLEQFLSILPKDLQ---AWV 101

  Fly    75 EKQGKQEDSDTETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKKVDGVPLKTVETPIYPLV 139
            .....:...:..|..|.....|:.....:|   ...:||.||..:...: |.|.:::...::|
Human   102 RAHHPETGEEAVTVLEDLERELDEPGKQVP---GNSERRDILMDKLAPL-GRPYESLTVQLHP-- 160

  Fly   140 VPEIPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEE--PRTLQVIGEVQ 202
                                  .:.||..:......|.::..::..::.::|  |:..:.:||:.
Human   161 ----------------------KKTQLEQEAGKPQRNGDKTRTKNEELFQKEDMPKDKEFLGEIN 203

  Fly   203 KNRRK-----PRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFC 262
            ....|     |:||..:|.                        ..|::|...:|      |.|.|
Human   204 DRLNKDTPQHPKSKDIIEN------------------------EGRSEWQQRER------RRYKC 238

  Fly   263 DQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQ--HLLNLHVRIKHRGELPYVCKYCGKR 325
            |:|||:||...:.:.|.|.|.|.|.::|.||.: .|.|  ||:. |.|: |.|..||.||.|||.
Human   239 DECGKSFSHSSDLSKHRRTHTGEKPYKCDECGK-AFIQRSHLIG-HHRV-HTGVKPYKCKECGKD 300

  Fly   326 FDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQ 374
            |......:.|:|.|..   .:|:.|..|.:.|:.|:||..|..:||..:
Human   301 FSGRTGLIQHQRIHTG---EKPYECDECGRPFRVSSALIRHQRIHTANK 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	15/65 (23%)
		zf-C2H2	260..282	CDD:278523	10/21 (48%)
		C2H2 Zn finger	262..282	CDD:275368	9/19 (47%)
		C2H2 Zn finger	290..311	CDD:275368	9/22 (41%)
		COG5048	<298..>383	CDD:227381	29/79 (37%)
		C2H2 Zn finger	319..339	CDD:275368	8/19 (42%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		ZnF_U1	375..407	CDD:197732	87/374 (23%)
		C2H2 Zn finger	378..396	CDD:275368
ZSCAN16	NP_001307484.1	SCAN	37..148	CDD:128708	23/114 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	160..184		4/47 (9%)
		COG5048	<183..323	CDD:227381	49/175 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	205..226		5/44 (11%)
		C2H2 Zn finger	238..258	CDD:275368	9/19 (47%)
		C2H2 Zn finger	266..286	CDD:275368	9/22 (41%)
		C2H2 Zn finger	294..314	CDD:275368	8/19 (42%)
		zf-C2H2	320..342	CDD:306579	7/21 (33%)
		C2H2 Zn finger	322..342	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050