DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF669

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_079080.2 Gene:ZNF669 / 79862 HGNCID:25736 Length:464 Species:Homo sapiens


Alignment Length:319 Identity:85/319 - (26%)
Similarity:128/319 - (40%) Gaps:79/319 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   151 PLRCEDPIQVKSEPQLSSDYPVESMNHEEPA-------SEMPQVMKEEPRTLQVIGEVQKNRRKP 208
            |..|.:|:....:..::.:....:...||.|       :...:||:|..|.|..:|...|::.  
Human    75 PEPCREPLASPIQDSVAFEDVAVNFTQEEWALLDSSQKNLYREVMQETCRNLASVGSQWKDQN-- 137

  Fly   209 RSKGCLE---ECPGKD---------------------MAKIENID-----STTNKTKE------- 237
                 :|   |.||||                     :::|.|:|     ||..|..|       
Human   138 -----IEDHFEKPGKDIRNHIVQRLCESKEDGQYGEVVSQIPNLDLNENISTGLKPCECSICGKV 197

  Fly   238 -EKYATRNKWGAAKRAY-ALEHRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQ 300
             .:::..|:...|...| ....:.|.|:||||.|........|:..|.|...::|..|.:..:..
Human   198 FVRHSLLNRHILAHSGYKPYGEKQYKCEQCGKFFVSVPGVRRHMIMHSGNPAYKCTICGKAFYFL 262

  Fly   301 HLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNHK-ESPV-------------------- 344
            :.:..|.| .|.||.||.||.|||.|......|.|||.|. |.|.                    
Human   263 NSVERHQR-THTGEKPYKCKQCGKAFTVSGSCLIHERTHTGEKPYECKECGKTFRFSCSFKTHER 326

  Fly   345 ----HRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATHYKSKH 399
                .||:.|:.|.|||..||:|:.|..:||||:|:.|:.|...|:|.::|..| :|.|
Human   327 THTGERPYKCTKCDKAFSCSTSLRYHGSIHTGERPYECKQCGKAFSRLSSLCNH-RSTH 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 8/21 (38%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
C2H2 Zn finger 290..311 CDD:275368 4/20 (20%)
COG5048 <298..>383 CDD:227381 38/109 (35%)
C2H2 Zn finger 319..339 CDD:275368 10/19 (53%)
C2H2 Zn finger 350..370 CDD:275368 9/19 (47%)
ZnF_U1 375..407 CDD:197732 9/25 (36%)
C2H2 Zn finger 378..396 CDD:275368 6/17 (35%)
ZNF669NP_079080.2 KRAB 90..>132 CDD:214630 9/41 (22%)
KRAB 90..129 CDD:279668 8/38 (21%)
C2H2 Zn finger 167..183 CDD:275368 3/15 (20%)
COG5048 <178..436 CDD:227381 63/209 (30%)
C2H2 Zn finger 191..211 CDD:275368 1/19 (5%)
C2H2 Zn finger 252..272 CDD:275368 4/20 (20%)
zf-H2C2_2 264..288 CDD:290200 12/24 (50%)
C2H2 Zn finger 280..300 CDD:275368 10/19 (53%)
zf-H2C2_2 296..315 CDD:290200 6/18 (33%)
C2H2 Zn finger 308..328 CDD:275368 0/19 (0%)
zf-H2C2_2 320..345 CDD:290200 7/24 (29%)
C2H2 Zn finger 336..356 CDD:275368 9/19 (47%)
zf-H2C2_2 348..373 CDD:290200 10/24 (42%)
C2H2 Zn finger 364..384 CDD:275368 7/20 (35%)
zf-H2C2_2 379..401 CDD:290200 3/7 (43%)
C2H2 Zn finger 392..412 CDD:275368
zf-H2C2_2 408..429 CDD:290200
C2H2 Zn finger 420..440 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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