DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF75D

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_009062.2 Gene:ZNF75D / 7626 HGNCID:13145 Length:510 Species:Homo sapiens


Alignment Length:287 Identity:79/287 - (27%)
Similarity:118/287 - (41%) Gaps:49/287 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   128 LKTVETPIYPLVVPEIPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEP 192
            |..:|..:|..|:.:|....:        .:.:|.:....:|:|:.....|              
Human   252 LNPLEKTLYNDVMQDIYETVI--------SLGLKLKNDTGNDHPISVSTSE-------------- 294

  Fly   193 RTLQVIG-EV-QKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYAT-----------RN 244
              :|..| || :|.|.|...|....|.|| |...::.......:.|.:|.||           ..
Human   295 --IQTSGCEVSKKTRMKIAQKTMGRENPG-DTHSVQKWHRAFPRKKRKKPATCKQELPKLMDLHG 356

  Fly   245 KWGAAKRAYALEHRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRI 309
            |....::.:.       |.:|||:|....:...|.|.|.|.|.::||:|||.......||.|. :
Human   357 KGPTGEKPFK-------CQECGKSFRVSSDLIKHHRIHTGEKPYKCQQCDRRFRWSSDLNKHF-M 413

  Fly   310 KHRGELPYVCKYCGKRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQ 374
            .|:|..||.|.:|||.|.:......|:|.|..   .:|..|..|.|.|..::.|..|...|||||
Human   414 THQGIKPYRCSWCGKSFSHNTNLHTHQRIHTG---EKPFKCDECGKRFIQNSHLIKHQRTHTGEQ 475

  Fly   375 PFHCELCQTFFNRRNALATHYKSKHHR 401
            |:.|.||:..|:||::|..|.|....|
Human   476 PYTCSLCKRNFSRRSSLLRHQKLHRRR 502

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 7/21 (33%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
C2H2 Zn finger 290..311 CDD:275368 8/20 (40%)
COG5048 <298..>383 CDD:227381 31/84 (37%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 6/19 (32%)
ZnF_U1 375..407 CDD:197732 11/27 (41%)
C2H2 Zn finger 378..396 CDD:275368 8/17 (47%)
ZNF75DNP_009062.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
SCAN 45..133 CDD:307924
KRAB 234..275 CDD:307490 5/30 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 313..343 7/30 (23%)
zf-C2H2 365..387 CDD:306579 7/28 (25%)
C2H2 Zn finger 367..387 CDD:275368 7/19 (37%)
COG5048 <378..>492 CDD:227381 44/117 (38%)
C2H2 Zn finger 395..415 CDD:275368 8/20 (40%)
C2H2 Zn finger 423..443 CDD:275368 7/19 (37%)
C2H2 Zn finger 451..471 CDD:275368 6/19 (32%)
C2H2 Zn finger 479..499 CDD:275368 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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