DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF18

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001290210.1 Gene:ZNF18 / 7566 HGNCID:12969 Length:549 Species:Homo sapiens


Alignment Length:386 Identity:92/386 - (23%)
Similarity:144/386 - (37%) Gaps:95/386 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 QEDSDTE-----TAREGGNNRLESRV--------DVMPISIAQPQRR--------------RILP 117
            :|:||||     .|.:..  |||.|:        .::|   |.||.:              .:|.
Human   183 KEESDTEAELALAASQPA--RLEERLIRDQDLGASLLP---AAPQEQWRQLDSTQKEQYWDLMLE 242

  Fly   118 QRSKKVDGVPL--------KTVE-----TPIYPLVVPEIPPADLVDPLRCEDPIQVKSEP----- 164
            ...|.|.|..:        .::|     ..||..|..:||....:...:..|...:..|.     
Human   243 TYGKMVSGAGISHPKSDLTNSIEFGEELAGIYLHVNEKIPRPTCIGDRQENDKENLNLENHRDQE 307

  Fly   165 ------QLSSDYPVES-----MNHEEP-----ASEMPQVMK--EEPRTLQVIGEVQKNRRKPRSK 211
                  |.|.:.|.::     ...:||     ...:|:.::  ::..|    ||....:.:...|
Human   308 LLHASCQASGEVPSQASLRGFFTEDEPGCFGEGENLPEALQNIQDEGT----GEQLSPQERISEK 368

  Fly   212 GCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFCDQCGKTFSEKGNFN 276
            ...:..|.....::..:      ..|||..|..|  ...|| .:..:|..|.:|||||.......
Human   369 QLGQHLPNPHSGEMSTM------WLEEKRETSQK--GQPRA-PMAQKLPTCRECGKTFYRNSQLI 424

  Fly   277 VHLRRHKGTKEFQCQECDR-----MEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHE 336
            .|.|.|.|...|||..|.:     .:|.:|      :..|.||.|..|.||||.|.:.....:||
Human   425 FHQRTHTGETYFQCTICKKAFLRSSDFVKH------QRTHTGEKPCKCDYCGKGFSDFSGLRHHE 483

  Fly   337 RNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATHYKS 397
            :.|..   .:|:.|..|:|:|...:....|..|||||:|:.|..|...|:..::|..|.:|
Human   484 KIHTG---EKPYKCPICEKSFIQRSNFNRHQRVHTGEKPYKCSHCGKSFSWSSSLDKHQRS 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 8/21 (38%)
C2H2 Zn finger 262..282 CDD:275368 8/19 (42%)
C2H2 Zn finger 290..311 CDD:275368 4/25 (16%)
COG5048 <298..>383 CDD:227381 29/84 (35%)
C2H2 Zn finger 319..339 CDD:275368 8/19 (42%)
C2H2 Zn finger 350..370 CDD:275368 5/19 (26%)
ZnF_U1 375..407 CDD:197732 7/23 (30%)
C2H2 Zn finger 378..396 CDD:275368 5/17 (29%)
ZNF18NP_001290210.1 SCAN 37..148 CDD:322011
KRAB <222..249 CDD:307490 3/26 (12%)
C2H2 Zn finger 410..430 CDD:275368 8/19 (42%)
COG5048 <436..549 CDD:227381 37/115 (32%)
C2H2 Zn finger 438..458 CDD:275368 4/25 (16%)
C2H2 Zn finger 466..486 CDD:275368 8/19 (42%)
zf-H2C2_2 479..503 CDD:316026 8/26 (31%)
C2H2 Zn finger 494..514 CDD:275368 5/19 (26%)
zf-H2C2_2 506..530 CDD:316026 9/23 (39%)
C2H2 Zn finger 522..542 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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