DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF735

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001152996.1 Gene:ZNF735 / 730291 HGNCID:32466 Length:412 Species:Homo sapiens


Alignment Length:320 Identity:88/320 - (27%)
Similarity:136/320 - (42%) Gaps:62/320 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 DPLRCEDPIQVKSEPQ------LSSDYPVESMNHEEPASEMPQVMKEE-----PRTLQVIGEVQK 203
            |.:.|   ::...|||      :::.:|| :.:|.....:..|.:|:.     |||....|....
Human    63 DLIAC---LEQNKEPQNIKRNEMAAKHPV-TCSHFNQDLQPEQSIKDSLQKVIPRTYGKCGHENL 123

  Fly   204 NRRK--PRSKGC---------LEECPG-------------KDMAKIENIDSTTNKTKEEKYATRN 244
            ..:|  .|...|         |.:|..             |..:|..|.:....:...:|:....
Human   124 QLKKCCKRVDECEVHKGGYNDLNQCLSNTQNKIFQTHKCVKVFSKFSNSNRHNARYTGKKHLKCK 188

  Fly   245 KWGAAKRAYAL-----EHRL-------YFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRME 297
            |:|   :::.:     :|::       |.|::|||:|:...:...|.|...|.|.::|:||.:..
Human   189 KYG---KSFCMFSHLNQHQIIHTKEKSYKCEECGKSFNHSSSGTTHKRILTGEKPYRCEECGKAF 250

  Fly   298 FTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTA 362
            .....|..|.|| |.||.||.|:.||:.|.......||:|.|..   .||:.|..|.|||..|:|
Human   251 RWPSNLTRHKRI-HTGEKPYACEECGQAFRRSSTLTNHKRIHTG---ERPYKCEECGKAFSVSSA 311

  Fly   363 LKDHIVVHTGEQPFHCELCQTFFNRRNALATHYKSKHHRLK---VEEQSKMPKMDATVQA 419
            |..|..:||||:|:.||.|...||..:.|.|| |..|...|   .||..:.....:||:|
Human   312 LIYHKRIHTGEKPYTCEECGKAFNCSSTLKTH-KIIHTGEKPYTCEECGRTFNCSSTVKA 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 8/21 (38%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
C2H2 Zn finger 290..311 CDD:275368 7/20 (35%)
COG5048 <298..>383 CDD:227381 36/84 (43%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 9/19 (47%)
ZnF_U1 375..407 CDD:197732 13/34 (38%)
C2H2 Zn finger 378..396 CDD:275368 8/17 (47%)
ZNF735NP_001152996.1 KRAB 16..76 CDD:214630 4/15 (27%)
KRAB 16..55 CDD:279668
C2H2 Zn finger 160..179 CDD:275368 3/18 (17%)
COG5048 <167..372 CDD:227381 68/212 (32%)
C2H2 Zn finger 187..207 CDD:275368 3/22 (14%)
zf-H2C2_2 199..224 CDD:290200 7/24 (29%)
C2H2 Zn finger 215..235 CDD:275368 7/19 (37%)
C2H2 Zn finger 243..263 CDD:275368 7/20 (35%)
zf-H2C2_2 255..280 CDD:290200 13/25 (52%)
C2H2 Zn finger 271..291 CDD:275368 7/19 (37%)
zf-H2C2_2 284..307 CDD:290200 10/25 (40%)
C2H2 Zn finger 299..319 CDD:275368 9/19 (47%)
zf-H2C2_2 311..336 CDD:290200 12/24 (50%)
C2H2 Zn finger 327..347 CDD:275368 9/20 (45%)
zf-H2C2_2 340..364 CDD:290200 8/24 (33%)
COG5048 <351..>412 CDD:227381 6/20 (30%)
C2H2 Zn finger 355..375 CDD:275368 5/16 (31%)
zf-H2C2_2 368..391 CDD:290200 2/3 (67%)
C2H2 Zn finger 383..403 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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