DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF736

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001164376.1 Gene:ZNF736 / 728927 HGNCID:32467 Length:427 Species:Homo sapiens


Alignment Length:223 Identity:72/223 - (32%)
Similarity:98/223 - (43%) Gaps:50/223 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   215 EECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFCDQCGKTFSEKGNFNVHL 279
            ||| |||.....:.             ||:     |:.:.:| |.|.|::|||.|.:..|...|.
Human   176 EEC-GKDCRLFSDF-------------TRH-----KKIHTVE-RCYKCEECGKAFKKFSNLTEHK 220

  Fly   280 RRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRL-NHERNH---- 339
            |.|.|.|.::|:.|.:.......|..|.| .|.|:.||.|:.|||.| .|...| ||:|.|    
Human   221 RVHTGEKPYKCEGCGKTFTCSSTLVKHKR-NHTGDRPYKCEECGKAF-KCFSDLTNHKRIHTGEK 283

  Fly   340 ------------------KESPVH---RPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQT 383
                              |...:|   :|:.|:.|.||||..:||..|..:||||:|:.||.|..
Human   284 PYKCEECNKAYRWFSDLAKHKIIHTGDKPYTCNECGKAFKWFSALSKHKRIHTGEKPYICEECGK 348

  Fly   384 FFNRRNALATHYK--SKHHRLKVEEQSK 409
            .|.|.:.|..|.:  .:....|.||.||
Human   349 AFTRSSTLFNHKRIHMEERPYKCEECSK 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 9/21 (43%)
C2H2 Zn finger 262..282 CDD:275368 8/19 (42%)
C2H2 Zn finger 290..311 CDD:275368 5/20 (25%)
COG5048 <298..>383 CDD:227381 38/110 (35%)
C2H2 Zn finger 319..339 CDD:275368 10/20 (50%)
C2H2 Zn finger 350..370 CDD:275368 9/19 (47%)
ZnF_U1 375..407 CDD:197732 10/33 (30%)
C2H2 Zn finger 378..396 CDD:275368 7/17 (41%)
ZNF736NP_001164376.1 KRAB 4..63 CDD:214630
KRAB 4..43 CDD:279668
C2H2 Zn finger 147..167 CDD:275368
C2H2 Zn finger 175..195 CDD:275368 9/37 (24%)
C2H2 Zn finger 203..223 CDD:275368 8/19 (42%)
zf-H2C2_2 215..240 CDD:290200 8/24 (33%)
COG5048 <227..383 CDD:227381 50/152 (33%)
C2H2 Zn finger 231..251 CDD:275368 5/20 (25%)
zf-H2C2_2 244..268 CDD:290200 12/25 (48%)
C2H2 Zn finger 259..279 CDD:275368 10/20 (50%)
zf-H2C2_2 271..294 CDD:290200 5/22 (23%)
C2H2 Zn finger 287..307 CDD:275368 1/19 (5%)
C2H2 Zn finger 315..335 CDD:275368 9/19 (47%)
zf-H2C2_2 327..352 CDD:290200 12/24 (50%)
C2H2 Zn finger 343..363 CDD:275368 7/19 (37%)
C2H2 Zn finger 371..391 CDD:275368 4/6 (67%)
zf-H2C2_2 383..407 CDD:290200
C2H2 Zn finger 399..419 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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