DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and ZSCAN31

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001128687.1	Gene:	ZSCAN31 / 64288	HGNCID:	14097	Length:	406	Species:	Homo sapiens

Alignment Length:	415	Identity:	112/415 - (26%)
Similarity:	180/415 - (43%)	Gaps:	76/415 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GQEAEHAKSLFDK-------EARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFRERC 66
            ||||  ::.||.:       ..|:.||.:.:|...|||  |.:.|:..:..||.|...:......
Human    34 GQEA--SRQLFRQFCYQETPGPREALSRLRELCHQWLR--PEIHTKEQILELLVLEQFLTILPEE 94

  Fly    67 IRTNSSWFE----KQGKQ-----EDSDTETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKK 122
            ::   :|..    :.|::     ||.:.|.: |.||...:.......:.:             :.
Human    95 LQ---AWVREHHPESGEEAVAVVEDLEQELS-EPGNQAPDHEHGHSEVLL-------------ED 142

  Fly   123 VDGVPLKTVETPIYPLVVPEIPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQV 187
            |:.:.:|...|.|      ::.|  :|..||.|.....:.:.|.....|    .::|.||:. ::
Human   143 VEHLKVKQEPTDI------QLQP--MVTQLRYESFCLHQFQEQDGESIP----ENQELASKQ-EI 194

  Fly   188 MKEEPRTLQVIGEVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAA--K 250
            :||    ::.:|:.:..|.........|.|.....|:.:...||     .|:....|:.|.:  |
Human   195 LKE----MEHLGDSKLQRDVSLDSKYRETCKRDSKAEKQQAHST-----GERRHRCNECGKSFTK 250

  Fly   251 RAYALEH-------RLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVR 308
            .:..:||       :.|.|::|||.||.:.:.|.|.|.|.|.|.:||:||.:.....:.|..|.|
Human   251 SSVLIEHQRIHTGEKPYECEECGKAFSRRSSLNEHRRSHTGEKPYQCKECGKAFSASNGLTRHRR 315

  Fly   309 IKHRGELPYVCKYCGKRF--DNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHT 371
            | |.||.||.||.|||.|  .:||  :.|:|.|..   .:.:.|..|.|||..:..|..|:.|||
Human   316 I-HTGEKPYECKVCGKAFLLSSCL--VQHQRIHTG---EKRYQCRECGKAFIQNAGLFQHLRVHT 374

  Fly   372 GEQPFHCELCQTFFNRRNALATHYK 396
            ||:|:.|..|...|::|..|..|.|
Human   375 GEKPYQCSQCSKLFSKRTLLKKHQK 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	19/77 (25%)
		zf-C2H2	260..282	CDD:278523	10/21 (48%)
		C2H2 Zn finger	262..282	CDD:275368	9/19 (47%)
		C2H2 Zn finger	290..311	CDD:275368	7/20 (35%)
		COG5048	<298..>383	CDD:227381	35/86 (41%)
		C2H2 Zn finger	319..339	CDD:275368	10/21 (48%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		ZnF_U1	375..407	CDD:197732	8/22 (36%)
		C2H2 Zn finger	378..396	CDD:275368	6/17 (35%)
ZSCAN31	NP_001128687.1	SCAN	35..146	CDD:128708	26/131 (20%)
		SCAN	35..123	CDD:280241	22/95 (23%)
		COG5048	<156..397	CDD:227381	80/262 (31%)
		zf-C2H2	239..261	CDD:278523	5/21 (24%)
		C2H2 Zn finger	241..261	CDD:275368	5/19 (26%)
		zf-H2C2_2	254..278	CDD:290200	8/23 (35%)
		C2H2 Zn finger	269..289	CDD:275368	9/19 (47%)
		zf-H2C2_2	281..305	CDD:290200	10/23 (43%)
		C2H2 Zn finger	297..317	CDD:275368	7/20 (35%)
		zf-H2C2_2	310..332	CDD:290200	14/22 (64%)
		C2H2 Zn finger	325..345	CDD:275368	10/21 (48%)
		zf-H2C2_2	338..362	CDD:290200	9/28 (32%)
		C2H2 Zn finger	353..373	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	10/22 (45%)
		C2H2 Zn finger	381..401	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960