DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and ZNF350

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_016882583.1	Gene:	ZNF350 / 59348	HGNCID:	16656	Length:	574	Species:	Homo sapiens

Alignment Length:	274	Identity:	79/274 - (28%)
Similarity:	110/274 - (40%)	Gaps:	41/274 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 NHE--EPASEMPQVMKEEPRTLQVIGEVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEE 238
            |||  ..|.:.|...|......|.|....:..||........||....:.|....|.....|.|:
Human   210 NHERLHTAIKFPASQKLISTKSQFISPKHQKTRKLEKHHVCSECGKAFIKKSWLTDHQVMHTGEK 274

  Fly   239 KYATRNKWGAAKRAYAL-EH-------RLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDR 295
            .:.......|..|.:.| ||       :.|.|.:|||.|.:|...|:|.:.|.|.|.:.|.||.:
Human   275 PHRCSLCEKAFSRKFMLTEHQRTHTGEKPYECPECGKAFLKKSRLNIHQKTHTGEKPYICSECGK 339

  Fly   296 MEFTQHLLNLHVRIKHRGELPYVCKYCGKRF--DNCLKRLNHERNHKESPVHRPHVCSTCQKAFK 358
            ....:..|.:|.|| |.||.||:|..|||.|  ..||  :.|:|.|...   .|.|||.|.|:..
Human   340 GFIQKGNLIVHQRI-HTGEKPYICNECGKGFIQKTCL--IAHQRFHTGK---TPFVCSECGKSCS 398

  Fly   359 TSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATHYKS-----------------------KHH 400
            ..:.|..|..:||||:||.|..|...|:.:..|..|.::                       ||.
Human   399 QKSGLIKHQRIHTGEKPFECSECGKAFSTKQKLIVHQRTHTGERPYGCNECGKAFAYMSCLVKHK 463

  Fly   401 RLKVEEQSKMPKMD 414
            |:...|:.:..|::
Human   464 RIHTREKQEAAKVE 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071
		zf-C2H2	260..282	CDD:278523	9/21 (43%)
		C2H2 Zn finger	262..282	CDD:275368	8/19 (42%)
		C2H2 Zn finger	290..311	CDD:275368	7/20 (35%)
		COG5048	<298..>383	CDD:227381	35/86 (41%)
		C2H2 Zn finger	319..339	CDD:275368	9/21 (43%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		ZnF_U1	375..407	CDD:197732	10/54 (19%)
		C2H2 Zn finger	378..396	CDD:275368	5/17 (29%)
ZNF350	XP_016882583.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050