DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and ZNF302

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_016882467.1	Gene:	ZNF302 / 55900	HGNCID:	13848	Length:	444	Species:	Homo sapiens

Alignment Length:	270	Identity:	72/270 - (26%)
Similarity:	112/270 - (41%)	Gaps:	41/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 DLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPRTLQVIGEVQKNRRKPRS- 210
            |:.|.   :.|..|..|..:...|...:.|.....:|. ...:....:...:.|.|.|..:..|
Human   132 DIYDE---DSPQPVTMEKVVKQSYEFSNSNKNLEYTEC-DTFRSTFHSKSTLSEPQNNSAEGNSH 192

  Fly   211 -----KGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAA---KRAYAL-----EHRLYFC 262
                 |..|.:   |.:.|.|.|:.      .:|....||.|||   .::..|     ..::|.|
Human   193 KYDILKKNLSK---KSVIKSERING------GKKLLNSNKSGAAFNQSKSLTLPQTCNREKIYTC 248

  Fly   263 DQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDR-----MEFTQHLLNLHVRIKHRGELPYVCKYC 322
            .:|||.|.::...:.|.|.|.|.|.::|:||.:     ...|:|      :|.|.||.||.|..|
Human   249 SECGKAFGKQSILSRHWRIHTGEKPYECRECGKTFSHGSSLTRH------QISHSGEKPYKCIEC 307

  Fly   323 GKRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNR 387
            ||.|.:.....||:..|..   .:|:.|..|.|:|...:.|..|:.:||.|:.:.|.:|...|..
Human   308 GKAFSHGSSLTNHQSTHTG---EKPYECMNCGKSFSRVSLLIQHLRIHTQEKRYECRICGKAFIH 369

  Fly   388 RNALATHYKS 397
            .::|..|.||
Human   370 SSSLIHHQKS 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071
		zf-C2H2	260..282	CDD:278523	8/21 (38%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	6/25 (24%)
		COG5048	<298..>383	CDD:227381	28/84 (33%)
		C2H2 Zn finger	319..339	CDD:275368	7/19 (37%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		ZnF_U1	375..407	CDD:197732	7/23 (30%)
		C2H2 Zn finger	378..396	CDD:275368	5/17 (29%)
ZNF302	XP_016882467.1	KRAB	48..109	CDD:214630
		COG5048	<151..393	CDD:227381	67/248 (27%)
		C2H2 Zn finger	248..268	CDD:275368	7/19 (37%)
		C2H2 Zn finger	276..296	CDD:275368	6/25 (24%)
		C2H2 Zn finger	304..324	CDD:275368	7/19 (37%)
		C2H2 Zn finger	332..352	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	7/20 (35%)
		C2H2 Zn finger	388..408	CDD:275368
		C2H2 Zn finger	416..436	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050