DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17806 and ZNF701

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001166126.1 Gene:ZNF701 / 55762 HGNCID:25597 Length:531 Species:Homo sapiens


Alignment Length:225 Identity:71/225 - (31%)
Similarity:106/225 - (47%) Gaps:43/225 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   219 GKDMAKIENIDSTTNKTKEEKYATRNKWGA--AKRAYALEHRL-------YFCDQCGKTFSEKGN 274
            |||..:...:......|.|..| |.|:.|.  :..:..|.|:.       |.|::|||.|:::.|
Human   315 GKDFHQKRYLACHRCHTGENPY-TCNECGKTFSHNSALLVHKAIHTGEKPYKCNECGKVFNQQSN 378

  Fly   275 FNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNH 339
            ...|.|.|.|.|.::|:|||::...:..|..|.|| |.||.||.||.|.|.|    :|.:|...|
Human   379 LARHHRVHTGEKPYKCEECDKVFSRKSHLERHRRI-HTGEKPYKCKVCDKAF----RRDSHLAQH 438

  Fly   340 KESPVH---RPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATH------- 394
              :.:|   :|:.|:.|.|.|..:::|..|.|:||||:.:.|..|...||.::.||.|       
Human   439 --TVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKVFNHKSNLACHRRLHTGE 501

  Fly   395 --YK--------------SKHHRLKVEEQS 408
              ||              .:||||...::|
Human   502 KPYKCNECGKVFNRKSNLERHHRLHTGKKS 531

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 9/21 (43%)
C2H2 Zn finger 262..282 CDD:275368 8/19 (42%)
C2H2 Zn finger 290..311 CDD:275368 8/20 (40%)
COG5048 <298..>383 CDD:227381 32/87 (37%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 7/19 (37%)
ZnF_U1 375..407 CDD:197732 13/54 (24%)
C2H2 Zn finger 378..396 CDD:275368 7/26 (27%)
ZNF701NP_001166126.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..42
KRAB 74..>114 CDD:214630
KRAB 74..113 CDD:279668
C2H2 Zn finger 283..303 CDD:275368
zf-H2C2_2 296..320 CDD:290200 3/4 (75%)
C2H2 Zn finger 311..330 CDD:275368 3/14 (21%)
C2H2 Zn finger 338..358 CDD:275368 4/19 (21%)
zf-H2C2_2 350..375 CDD:290200 8/24 (33%)
C2H2 Zn finger 366..386 CDD:275368 8/19 (42%)
zf-H2C2_2 378..403 CDD:290200 10/24 (42%)
COG5048 <390..527 CDD:227381 48/143 (34%)
C2H2 Zn finger 394..414 CDD:275368 8/20 (40%)
zf-H2C2_2 406..431 CDD:290200 14/29 (48%)
C2H2 Zn finger 422..442 CDD:275368 8/25 (32%)
zf-H2C2_2 434..459 CDD:290200 8/26 (31%)
C2H2 Zn finger 450..470 CDD:275368 7/19 (37%)
zf-H2C2_2 462..487 CDD:290200 10/24 (42%)
C2H2 Zn finger 478..498 CDD:275368 7/19 (37%)
zf-H2C2_2 490..515 CDD:290200 5/24 (21%)
C2H2 Zn finger 506..526 CDD:275368 3/19 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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