DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF506

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001092739.1 Gene:ZNF506 / 440515 HGNCID:23780 Length:444 Species:Homo sapiens


Alignment Length:292 Identity:83/292 - (28%)
Similarity:127/292 - (43%) Gaps:66/292 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 RC-EDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPRTLQVIGEVQK--------NRRKP 208
            :| .|.:|:|...:...:.||    |:...:.:.|.:....|.:....|..|        |:.|.
Human   105 KCRHDNLQLKKGCESVDECPV----HKRGYNGLKQCLATTQRKIFQCDEYVKFLHKFSNSNKHKI 165

  Fly   209 RSKG-----CLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFCDQCGKT 268
            |..|     |:|.  ||          |.|::     :||..:   |:..|.|.| |.|::|||.
Human   166 RDTGKKSFKCIEY--GK----------TFNQS-----STRTTY---KKIDAGEKR-YKCEECGKA 209

  Fly   269 FSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRL 333
            :.:..:...|.:.|.|.|.::|:||.:.......|..| :|.|.||.||.|:.|||.|::.....
Human   210 YKQSSHLTTHKKIHTGEKPYKCEECGKAYKQSCNLTTH-KIIHTGEKPYRCRECGKAFNHPATLF 273

  Fly   334 NHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATH---- 394
            :|::.|..   .:|:.|..|.|||.:|:.|..|.::||||:|:.||.|...|||.:.|..|    
Human   274 SHKKIHTG---EKPYKCDKCGKAFISSSTLTKHEIIHTGEKPYKCEECGKAFNRSSNLTKHKRIH 335

  Fly   395 -----YK--------------SKHHRLKVEEQ 407
                 ||              |||.|....|:
Human   336 TGDVPYKCDECGKTFTWYSSLSKHKRAHTGEK 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 6/21 (29%)
C2H2 Zn finger 262..282 CDD:275368 5/19 (26%)
C2H2 Zn finger 290..311 CDD:275368 6/20 (30%)
COG5048 <298..>383 CDD:227381 32/84 (38%)
C2H2 Zn finger 319..339 CDD:275368 6/19 (32%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
ZnF_U1 375..407 CDD:197732 15/54 (28%)
C2H2 Zn finger 378..396 CDD:275368 8/26 (31%)
ZNF506NP_001092739.1 KRAB 4..62 CDD:214630
KRAB 6..43 CDD:279668
C2H2 Zn finger 147..167 CDD:275368 4/19 (21%)
C2H2 Zn finger 175..195 CDD:275368 9/39 (23%)
C2H2 Zn finger 203..223 CDD:275368 5/19 (26%)
zf-H2C2_2 215..240 CDD:290200 7/24 (29%)
C2H2 Zn finger 231..251 CDD:275368 6/20 (30%)
zf-H2C2_2 243..268 CDD:290200 13/25 (52%)
COG5048 <255..417 CDD:227381 38/116 (33%)
C2H2 Zn finger 259..279 CDD:275368 6/19 (32%)
zf-H2C2_2 272..296 CDD:290200 8/26 (31%)
C2H2 Zn finger 287..307 CDD:275368 8/19 (42%)
zf-H2C2_2 300..324 CDD:290200 11/23 (48%)
C2H2 Zn finger 315..335 CDD:275368 8/19 (42%)
zf-H2C2_2 327..351 CDD:290200 4/23 (17%)
C2H2 Zn finger 343..363 CDD:275368 4/19 (21%)
zf-H2C2_2 355..379 CDD:290200 5/13 (38%)
C2H2 Zn finger 371..391 CDD:275368
zf-H2C2_2 384..407 CDD:290200
C2H2 Zn finger 399..419 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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