DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and CG4854

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	399	Identity:	100/399 - (25%)
Similarity:	145/399 - (36%)	Gaps:	94/399 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGQEAEHAKSLFDKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFRERCIRT 69
            ||.|..:.:. :||...|. |....|.:.||..|...|..|.|||.||.|.|..|:..|..|.:|
  Fly    12 CRICLVQPKD-ESLMPTEP-DFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLCQQT 74

  Fly    70 NSSWFEKQGKQEDSDTETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKKVDGVPLKTVETP 134
                 ||..|                 |.::..:.|.|...:      |.:||         :|.
  Fly    75 -----EKDLK-----------------EQKLQEINIEIVHDE------QETKK---------KTE 102

  Fly   135 IYPLVVPEIPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPRTLQVIG 199
            ...|...|...:|            .:.|.:....|.|...:.|:.|....:::..||.......
  Fly   103 SRDLSKNEATGSD------------SELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEE 155

  Fly   200 EVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFCDQ 264
            .|.....||              ...|:.||                |.|..        :.|:.
  Fly   156 SVYSLSPKP--------------VTFEDEDS----------------GQAAS--------FTCNI 182

  Fly   265 CGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNC 329
            |...:||:.....|::.|...|..:|:.|.:.......|..|:. .|.|..||.|.||..||.:.
  Fly   183 CNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMN-THTGNRPYKCDYCDSRFADP 246

  Fly   330 LKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATH 394
            ..|:.|:|.|..   .||:.|..|.::|..|..|:.|:..||||:||.|:.||..|::.:...:|
  Fly   247 STRIKHQRIHTN---ERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSH 308

  Fly   395 YKSKHHRLK 403
            .|| |.|.|
  Fly   309 EKS-HKRTK 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	24/70 (34%)
		zf-C2H2	260..282	CDD:278523	5/21 (24%)
		C2H2 Zn finger	262..282	CDD:275368	5/19 (26%)
		C2H2 Zn finger	290..311	CDD:275368	4/20 (20%)
		COG5048	<298..>383	CDD:227381	31/84 (37%)
		C2H2 Zn finger	319..339	CDD:275368	8/19 (42%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		ZnF_U1	375..407	CDD:197732	12/29 (41%)
		C2H2 Zn finger	378..396	CDD:275368	5/17 (29%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	16/46 (35%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	193..217	CDD:290200	5/23 (22%)
		COG5048	201..>258	CDD:227381	18/57 (32%)
		C2H2 Zn finger	208..228	CDD:275368	4/20 (20%)
		zf-H2C2_2	221..244	CDD:290200	10/23 (43%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	251..273	CDD:290200	8/24 (33%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	12/23 (52%)
		C2H2 Zn finger	292..312	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960