DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and Odj

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	123/435 - (28%)
Similarity:	176/435 - (40%)	Gaps:	84/435 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTTLCRTCGQE--AEHAKSLFDKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFR 63
            |:|.||.||:.  ..|.|::|:|....:...|.::||..:..:..:|..||..|||||..|:|||
  Fly     1 MSTECRICGERIFTPHPKNIFEKRNHRIRMAIEQITGLEIVLENMLPQHICACCLLDLTQAVAFR 65

  Fly    64 ERCIRTNSSWFEKQGKQEDSDTETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKKVDGVPL 128
            :||:.|:::                                           |.||.....||..
  Fly    66 QRCLETHAN-------------------------------------------LHQRISSKAGVAS 87

  Fly   129 KTVETPIYPLVVPEIPPADLVDPLR----CEDPIQVKSEPQLSS------DYPVESMNHEEPASE 183
            |.         .||:.|. |.|||.    .:|.:..:.:.:|..      |...:.:..|:|...
  Fly    88 KG---------SPEVSPV-LSDPLLKREVLDDTVDTEDDKELLDDDKDLMDDDKDFLEDEKPILR 142

  Fly   184 MPQVMKEEPRTLQVIGEVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGA 248
            .|...|     :::..:...||:.||.:......|     .:|..||.....:|.....|.:...
  Fly   143 YPPAKK-----IRIEDQNFPNRQSPRVRVKRLRVP-----VVEKADSPPPPPREHVRKPRKRRPK 197

  Fly   249 AKRAYALEHRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRG 313
            .|...:::.  |.|||||.:|::..|...|..||...| |.|.||.|..:|..||.||:|:.|:|
  Fly   198 PKVDRSIKR--YVCDQCGWSFNDHSNMKDHKLRHFEEK-FSCDECGRKFYTMPLLRLHIRVHHKG 259

  Fly   314 ELPYVCKYCGKRFDNCLKRLNHERN-HKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQP-F 376
            |.|||||:||..|.|...|..|||. |....|   |.|..|.|.|.:......|...|..:|| .
  Fly   260 EKPYVCKFCGMGFANSPSRCRHERQMHANELV---HPCKICGKRFNSEKGRLKHEEGHKSDQPDV 321

  Fly   377 H-CELCQTFFNRRNALATHYKSKHHRLKVEEQSKMPKMDATVQAD 420
            | |..|...|.....|..||.:|:||.:|......||.:...:.|
  Fly   322 HICLTCNKEFKEAQFLHRHYSTKYHRKRVNLLVNGPKEEFQSEVD 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	26/73 (36%)
		zf-C2H2	260..282	CDD:278523	9/21 (43%)
		C2H2 Zn finger	262..282	CDD:275368	8/19 (42%)
		C2H2 Zn finger	290..311	CDD:275368	10/20 (50%)
		COG5048	<298..>383	CDD:227381	36/87 (41%)
		C2H2 Zn finger	319..339	CDD:275368	10/20 (50%)
		C2H2 Zn finger	350..370	CDD:275368	5/19 (26%)
		ZnF_U1	375..407	CDD:197732	12/33 (36%)
		C2H2 Zn finger	378..396	CDD:275368	5/17 (29%)
Odj	NP_650661.1	zf-AD	5..77	CDD:214871	27/114 (24%)
		COG5048	<202..343	CDD:227381	57/146 (39%)
		C2H2 Zn finger	209..229	CDD:275368	8/19 (42%)
		C2H2 Zn finger	236..256	CDD:275368	10/19 (53%)
		zf-H2C2_2	249..274	CDD:290200	15/24 (63%)
		C2H2 Zn finger	265..283	CDD:275368	8/17 (47%)
		C2H2 Zn finger	298..314	CDD:275368	3/15 (20%)
		zf-C2H2_jaz	322..347	CDD:288983	8/24 (33%)
		C2H2 Zn finger	324..343	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450090
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.890