DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17806 and CG17801

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	108/425 - (25%)
Similarity:	169/425 - (39%)	Gaps:	116/425 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFRERCIRTNS------------------ 71
            :||:.|..|||.||......|..||.|||.|||.:|..::|..|.::
  Fly    29 EVLAKIKDLTGIWLEQNERQPRHICPSCLNDLNTSIKLKKRIQRVHNEATLRRESGLDEDLESTV 93

  Fly    72 SWFEKQGKQEDSDTETAREGGNNRLESRVDV--MPISIAQPQRRRILPQRSKKVDGVPLKTVETP 134
            |..|.:|...|.::|.:.:..|...:.:.:.  :.:::|...||.   :.....|.      |||
  Fly    94 SDIEPEGDSSDLESEESYDSENYPFDKKAEESDIDLNLAHEDRRN---EPHNPYDS------ETP 149

  Fly   135 IY-----PLV-VPEIPPADLVDPLRCEDP-----IQVKSEPQLSSDYPVESMNHEEPASEMPQVM 188
            :.     ||: .|.....:|.:.:..:.|     ||:.::.:|.:.||  |:...:|.:..|:
  Fly   150 LIFKHKNPLIETPSFANENLPNKVDAKSPKKGNFIQIGTDLRLLTTYP--SIKVVKPLALAPE-- 210

  Fly   189 KEEPRTLQVIGEVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAY 253
                                            |:| .||:.                  .|||.
  Fly   211 --------------------------------DVA-AENVP------------------PAKRT- 223

  Fly   254 ALEHRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYV 318
            |.:.:...|.:||:.|....|...|:.||.|.|.|.|..||:...|::|..||.|::|.||.|:.
  Fly   224 ARKMQSLVCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTFCDKRFVTKYLARLHERVRHMGEQPFE 288

  Fly   319 CKYCGKRFDNCLKRLNHERNHKESPVHRPHV------CSTCQKAFKTSTALKDHIVVHTGEQPFH 377
            |.:|...|.....:.:|||..        |:      |..|.|.|.|.|.|..|..:|:|.:||.
  Fly   289 CNFCSATFFTSTAKSSHERIR--------HIRDLRYQCDQCTKRFNTKTCLNKHKFLHSGLKPFD 345

  Fly   378 CELCQTFFNRRNALATHYKSKHHR------LKVEE 406
            |.:||..|.|:..|.:|:.|..|:      |:.||
  Fly   346 CVICQINFARKATLRSHFDSVAHQKRASAILESEE 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	21/68 (31%)
		zf-C2H2	260..282	CDD:278523	6/21 (29%)
		C2H2 Zn finger	262..282	CDD:275368	6/19 (32%)
		C2H2 Zn finger	290..311	CDD:275368	8/20 (40%)
		COG5048	<298..>383	CDD:227381	30/90 (33%)
		C2H2 Zn finger	319..339	CDD:275368	6/19 (32%)
		C2H2 Zn finger	350..370	CDD:275368	8/19 (42%)
		ZnF_U1	375..407	CDD:197732	14/38 (37%)
		C2H2 Zn finger	378..396	CDD:275368	7/17 (41%)
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	20/44 (45%)
		zf-C2H2	231..252	CDD:278523	6/20 (30%)
		C2H2 Zn finger	232..252	CDD:275368	6/19 (32%)
		zf-H2C2_2	244..269	CDD:290200	10/24 (42%)
		C2H2 Zn finger	260..281	CDD:275368	8/20 (40%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	318..338	CDD:275368	8/19 (42%)
		C2H2 Zn finger	346..362	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3C61Y
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.760