DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and CG14710

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	108/453 - (23%)
Similarity:	175/453 - (38%)	Gaps:	109/453 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGQEAEHAK--SLF-DKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFRERC 66
            ||.|..:.|.::  .|| ||...|:...:.......:|..|.:|.:.|.||...:.....||:.|
  Fly    10 CRICLGDFEESQMICLFGDKGESDLRKKLELCCRIRVRQSPQLPEKACNSCCEFVQMWFNFRQMC 74

  Fly    67 IRTNSSWFEKQGKQED-----SDTE-----------------------TAREGGNNRLESRVDVM 103
            :.:...|.....::.:     ||.|                       ||.|.|:.:.|.
  Fly    75 LNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGTENQEKEEITAIEEGDEQQED----- 134

  Fly   104 PISIAQPQRRRILP------QRSKKVDGVPLKTVETPIYPLVVPEIPPADLVDPLRCEDPIQVKS 162
                   |.:.:|.      ..|.:.|..|  ..|:| ..:::..:.  ..||..:.|:.|..|.
  Fly   135 -------QSQEVLDFNGFIINESIEEDEEP--NTESP-EQILISHMD--SYVDDQQMEELIDDKG 187

  Fly   163 E--PQLSSD---YPVESMNHEEPASEMP------QVMKEEPRTLQVIGEVQKNRRKPRSKGCLEE 216
            |  .:||:.   |.||..:.|...|..|      ::.|::|             .:||......:
  Fly   188 ELVEELSNANTFYEVEYGDEELLMSSAPSPHPSFKMDKQKP-------------GRPRKPDAELK 239

  Fly   217 CPGKDMAKIENIDSTTNKTK---EEKYATRNKWGAAKRAYALEHRLYFCDQCGKTFSEKGNFNVH 278
            ...||:    |.....|:.|   |||                    :.|..||..|.:|..|..|
  Fly   240 FKRKDI----NAKERGNQPKCKEEEK--------------------FMCILCGNVFYKKSVFTAH 280

  Fly   279 LRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNHKESP 343
            :..|...|..||:.|::.......|..|:| :|.|:.||.|.||.:.|.:..:|:.|||.|..:
  Fly   281 MMTHSEYKPHQCEICNKSFRQMGELRAHIR-RHTGDRPYKCMYCDRHFYDRSERVRHERVHTNT- 343

  Fly   344 VHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATHYKSKHHRLKVEE 406
              ||:.|..|.|.|..:..||:||:.|:.::.::|.:|...|...:.|..|.::..||.|:|:
  Fly   344 --RPYACQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKAHLQTLTHRNKMEQ 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	19/73 (26%)
		zf-C2H2	260..282	CDD:278523	7/21 (33%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	5/20 (25%)
		COG5048	<298..>383	CDD:227381	29/84 (35%)
		C2H2 Zn finger	319..339	CDD:275368	8/19 (42%)
		C2H2 Zn finger	350..370	CDD:275368	8/19 (42%)
		ZnF_U1	375..407	CDD:197732	9/32 (28%)
		C2H2 Zn finger	378..396	CDD:275368	5/17 (29%)
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	19/72 (26%)
		COG5048	<261..395	CDD:227381	45/157 (29%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-C2H2	290..312	CDD:278523	6/22 (27%)
		C2H2 Zn finger	292..312	CDD:275368	5/20 (25%)
		zf-H2C2_2	304..327	CDD:290200	10/23 (43%)
		C2H2 Zn finger	320..340	CDD:275368	8/19 (42%)
		zf-H2C2_2	335..357	CDD:290200	10/24 (42%)
		C2H2 Zn finger	348..368	CDD:275368	8/19 (42%)
		C2H2 Zn finger	376..395	CDD:275368	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960