DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and CG8159

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	410	Identity:	117/410 - (28%)
Similarity:	181/410 - (44%)	Gaps:	81/410 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTTLCRTCGQEAEHAKS--LFDKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFR 63
            :..:||.|....:::||  ||:..|..||..|..|||..|:.:||:|..:|.:|..||..||:||
  Fly     2 LQNVCRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFR 66

  Fly    64 ERCIRTNSSWFEKQGKQEDSDTETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKKVDGVPL 128
            :||:|:... ||:...:.:.||          ..|.|           ||....||.:..|..|
  Fly    67 DRCLRSQKI-FEESLVRNEEDT----------FRSSV-----------RRSARSQRQRHEDTAP- 108

  Fly   129 KTVETPIYPLVVPEIPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPR 193
               :||..||                  .:.:|.|...:.|...:.::|.:..:|...
  Fly   109 ---KTPASPL------------------EVMIKLESLSNGDEEDDGIDHLDSCNEADM------- 145

  Fly   194 TLQVIGEVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATR--NKWGAAKRAYALE 256
                                  |...|.|:.....|.||:..:.::...|  .|.|..:....:.
  Fly   146 ----------------------ELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGGKGENRTKVT 188

  Fly   257 HRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKY 321
            ..::||||||...:.|.:|:.|||:|.|.:.|||:.|.....:...|..| ::.|.|:..:.|:|
  Fly   189 LPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGH-QVMHTGDRKFQCRY 252

  Fly   322 CGKRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFN 386
            |.:.:.|...||.|||.|...   ||.:|:.|.|:|..|..||:|:::||||:.|.||||...|.
  Fly   253 CDRTYVNYSGRLRHERTHTND---RPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFA 314

  Fly   387 RRNALATHYKSKHHRLKVEE 406
            |...|.||::|..|:..:|:
  Fly   315 RPTHLKTHFRSNTHKHNLEK 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	30/73 (41%)
		zf-C2H2	260..282	CDD:278523	11/21 (52%)
		C2H2 Zn finger	262..282	CDD:275368	10/19 (53%)
		C2H2 Zn finger	290..311	CDD:275368	4/20 (20%)
		COG5048	<298..>383	CDD:227381	33/84 (39%)
		C2H2 Zn finger	319..339	CDD:275368	9/19 (47%)
		C2H2 Zn finger	350..370	CDD:275368	8/19 (42%)
		ZnF_U1	375..407	CDD:197732	13/32 (41%)
		C2H2 Zn finger	378..396	CDD:275368	9/17 (53%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	30/73 (41%)
		C2H2 Zn finger	194..214	CDD:275368	10/19 (53%)
		COG5048	<197..322	CDD:227381	49/128 (38%)
		zf-H2C2_2	206..231	CDD:290200	10/24 (42%)
		C2H2 Zn finger	222..242	CDD:275368	4/20 (20%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		zf-H2C2_2	265..287	CDD:290200	10/24 (42%)
		C2H2 Zn finger	278..298	CDD:275368	8/19 (42%)
		zf-H2C2_2	291..315	CDD:290200	13/23 (57%)
		C2H2 Zn finger	306..328	CDD:275368	10/21 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860