DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and hb

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_731267.1	Gene:	hb / 41032	FlyBaseID:	FBgn0001180	Length:	758	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	69/304 - (22%)
Similarity:	99/304 - (32%)	Gaps:	96/304 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 GGNNRLESRVDVMPISIAQPQRR------RILPQRSKKVDGVPLKTVETPIYPLVVPE------- 142
            ||.|.|      .|..:..|.:.      |..||        |..|..:.|.|:.|..
  Fly   125 GGFNPL------TPPGLPNPMQHFYGGNLRPSPQ--------PTPTSASTIAPVAVATGSSEKLQ 175

  Fly   143 --IPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPRTLQVIGEVQKNR 205
              .||.|:..|          ..|..||...:|.....:..|...:.||.
  Fly   176 ALTPPMDVTPP----------KSPAKSSQSNIEPEKEHDQMSNSSEDMKY--------------- 215

  Fly   206 RKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFCDQCGKTFS 270
                            ||:.|:.|:..      :....|..|..|.        |.|..||....
  Fly   216 ----------------MAESEDDDTNI------RMPIYNSHGKMKN--------YKCKTCGVVAI 250

  Fly   271 EKGNFNVHLRRH-KGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKR-- 332
            .|.:|..|.|.| |..|..||.:|..:...:|.|..|:| ||:.:.|:.|..|..   .|:.:
  Fly   251 TKVDFWAHTRTHMKPDKILQCPKCPFVTEFKHHLEYHIR-KHKNQKPFQCDKCSY---TCVNKSM 311

  Fly   333 LN-HERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQP 375
            || |.::|.....:|   |:.|..|.|...:.|.|:..: |.:|
  Fly   312 LNSHRKSHSSVYQYR---CADCDYATKYCHSFKLHLRKY-GHKP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071
		zf-C2H2	260..282	CDD:278523	8/21 (38%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	6/20 (30%)
		COG5048	<298..>383	CDD:227381	23/81 (28%)
		C2H2 Zn finger	319..339	CDD:275368	6/22 (27%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		ZnF_U1	375..407	CDD:197732	1/1 (100%)
		C2H2 Zn finger	378..396	CDD:275368
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	7/19 (37%)
		C2H2 Zn finger	271..291	CDD:275368	6/20 (30%)
		zf-H2C2_2	283..308	CDD:290200	9/28 (32%)
		C2H2 Zn finger	299..319	CDD:275368	6/22 (27%)
		C2H2 Zn finger	327..345	CDD:275368	6/17 (35%)
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100