DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and CG11247

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	79/328 - (24%)
Similarity:	117/328 - (35%)	Gaps:	110/328 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 PQVMKEEPRTLQVIGEVQKNRRKPRSKGCLEECPGK-DMAK--IENIDSTTNKTKEEKYATRNKW 246
            ||:.|...:     ||..|.:....|: |.:|..|| |:.:  :.:.|...:|.|:...:.|...
  Fly    76 PQLKKSARK-----GEPVKRKHHVCSQ-CSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAV 134

  Fly   247 GAAKR-AYALEHRLYF-CDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRM-----EFTQHLL- 303
            ..... ..|.|||..| |.||.|:|:.|....:|:|.|.|.|.:.|..||:.     :..||::
  Fly   135 NLKNHITTAHEHRKQFVCSQCPKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVS 199

  Fly   304 ----------------------NLHVRI-KHRGELPYVCKYCGKRFDN----------------- 328
                                  ||.|.: :|...:.:.|..|..:|.|
  Fly   200 HHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQ 264

  Fly   329 -----CLKRL-------NHERNHKESPVH-------------------------RPHVCSTCQKA 356
                 |.|.:       .|.:.|.....|                         ||:.|..|.:.
  Fly   265 FECEICHKMIEPDEDLATHMQRHTAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQT 329

  Fly   357 FKTSTALKDHIVVHTGEQPFHCELC--QTFFNRRNALATHYKSKH--------------HRLKVE 405
            |..|:.||.||..||||:||.|:||  :..|::...|..|.|..|              .::|||
  Fly   330 FAHSSVLKLHIRKHTGEKPFRCQLCEDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVE 394

  Fly   406 EQS 408
            .||
  Fly   395 LQS 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071
		zf-C2H2	260..282	CDD:278523	9/22 (41%)
		C2H2 Zn finger	262..282	CDD:275368	8/19 (42%)
		C2H2 Zn finger	290..311	CDD:275368	8/49 (16%)
		COG5048	<298..>383	CDD:227381	34/164 (21%)
		C2H2 Zn finger	319..339	CDD:275368	7/48 (15%)
		C2H2 Zn finger	350..370	CDD:275368	8/19 (42%)
		ZnF_U1	375..407	CDD:197732	13/47 (28%)
		C2H2 Zn finger	378..396	CDD:275368	6/19 (32%)
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	39/159 (25%)
		C2H2 Zn finger	95..115	CDD:275368	6/20 (30%)
		zf-H2C2_2	107..132	CDD:290200	4/24 (17%)
		C2H2 Zn finger	123..144	CDD:275368	2/20 (10%)
		C2H2 Zn finger	152..172	CDD:275368	8/19 (42%)
		zf-H2C2_2	165..189	CDD:290200	8/23 (35%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		COG5048	<192..369	CDD:227381	36/176 (20%)
		C2H2 Zn finger	210..230	CDD:275370	3/19 (16%)
		C2H2 Zn finger	238..260	CDD:275371	4/21 (19%)
		C2H2 Zn finger	267..287	CDD:275368	3/19 (16%)
		C2H2 Zn finger	295..315	CDD:275368	0/19 (0%)
		zf-H2C2_2	309..332	CDD:290200	5/22 (23%)
		C2H2 Zn finger	323..343	CDD:275368	8/19 (42%)
		C2H2 Zn finger	351..374	CDD:275368	7/22 (32%)
		C2H2 Zn finger	382..399	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100