DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF789

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_998768.2 Gene:ZNF789 / 285989 HGNCID:27801 Length:425 Species:Homo sapiens


Alignment Length:268 Identity:69/268 - (25%)
Similarity:111/268 - (41%) Gaps:51/268 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   180 PASEMPQVMK---------EEPRTLQVIGEVQKNRRKPRSKGCLEEC-------------PGKDM 222
            |.||....||         |:..:.::...:|::..|...|  |.:|             .|.:.
Human    88 PGSEARHKMKKLTPKQKFSEDLESYKISVVMQESAEKLSEK--LHKCKEFVDSCRLTFPTSGDEY 150

  Fly   223 AK--IENIDSTTNKTKEEKYATRNKWGA--------AKRAYALEH-------RLYFCDQCGKTFS 270
            ::  ::|:    |..:::...||.|.|.        .:|:..|.|       :.|.|.:|||...
Human   151 SRGFLQNL----NLIQDQNAQTRWKQGRYDEDGKPFNQRSLLLGHERILTRAKSYECSECGKVIR 211

  Fly   271 EKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNH 335
            .|..|:.|.|.|.....|:|:.|.:....:..|.:|.:. |....||.|..|||.|......:.|
Human   212 RKAWFDQHQRIHFLENPFECKVCGQAFRQRSALTVHKQC-HLQNKPYRCHDCGKCFRQLAYLVEH 275

  Fly   336 ERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRRNALATHYK--SK 398
            :|.|.:   .:|:.||.|:|.|..::.|..|.|:|:||:...|..|...|.|.:.|..|.:  ||
Human   276 KRIHTK---EKPYKCSKCEKTFSQNSTLIRHQVIHSGEKRHKCLECGKAFGRHSTLLCHQQIHSK 337

  Fly   399 HHRLKVEE 406
            .:..|..|
Human   338 PNTHKCSE 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 9/21 (43%)
C2H2 Zn finger 262..282 CDD:275368 8/19 (42%)
C2H2 Zn finger 290..311 CDD:275368 4/20 (20%)
COG5048 <298..>383 CDD:227381 27/84 (32%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
ZnF_U1 375..407 CDD:197732 10/34 (29%)
C2H2 Zn finger 378..396 CDD:275368 6/17 (35%)
ZNF789NP_998768.2 KRAB 11..71 CDD:214630
KRAB 11..50 CDD:279668
COG5048 <179..303 CDD:227381 36/127 (28%)
C2H2 Zn finger 179..195 CDD:275368 3/15 (20%)
C2H2 Zn finger 203..223 CDD:275368 8/19 (42%)
C2H2 Zn finger 231..251 CDD:275368 4/20 (20%)
C2H2 Zn finger 259..279 CDD:275368 7/19 (37%)
zf-H2C2_2 271..296 CDD:290200 9/27 (33%)
COG5048 <283..420 CDD:227381 22/63 (35%)
C2H2 Zn finger 287..307 CDD:275368 8/19 (42%)
C2H2 Zn finger 315..335 CDD:275368 6/19 (32%)
C2H2 Zn finger 343..363 CDD:275368 1/3 (33%)
C2H2 Zn finger 371..391 CDD:275368
C2H2 Zn finger 399..419 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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