DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17806 and ZNF621

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001091884.1	Gene:	ZNF621 / 285268	HGNCID:	24787	Length:	439	Species:	Homo sapiens

Alignment Length:	160	Identity:	53/160 - (33%)
Similarity:	70/160 - (43%)	Gaps:	26/160 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 CDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRF 326
            |.:|||.|....:..||.:.|.|...::|:||.:...:...|..|.|| |.||.||.||.|||.|
Human   181 CKECGKAFKSSYDCIVHEKNHIGEGPYECKECGKGLSSNTALTQHQRI-HTGEKPYECKECGKAF 244

  Fly   327 DNCLKRLNHERNH--------KE--------------SPVH---RPHVCSTCQKAFKTSTALKDH 366
            ......|.|:|.|        ||              ..:|   :|:.|..|.|||....|...|
Human   245 RRSAAYLQHQRLHTGEKLYKCKECWKAFGCRSLFIVHQRIHTGEKPYQCKECGKAFTQKIASIQH 309

  Fly   367 IVVHTGEQPFHCELCQTFFNRRNALATHYK 396
            ..|||||:|:.|::|...|....:...|.|
Human   310 QRVHTGEKPYECKVCGKAFKWYGSFVQHQK 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071
		zf-C2H2	260..282	CDD:278523	7/19 (37%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	7/20 (35%)
		COG5048	<298..>383	CDD:227381	38/109 (35%)
		C2H2 Zn finger	319..339	CDD:275368	9/19 (47%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		ZnF_U1	375..407	CDD:197732	6/22 (27%)
		C2H2 Zn finger	378..396	CDD:275368	4/17 (24%)
ZNF621	NP_001091884.1	KRAB	11..71	CDD:214630
		COG4049	145..198	CDD:226535	6/16 (38%)
		C2H2 Zn finger	153..173	CDD:275368
		zf-H2C2_2	166..190	CDD:316026	5/8 (63%)
		C2H2 Zn finger	209..229	CDD:275368	7/20 (35%)
		zf-H2C2_2	221..246	CDD:316026	15/25 (60%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	265..285	CDD:275368	2/19 (11%)
		zf-H2C2_2	281..302	CDD:316026	7/20 (35%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
		zf-H2C2_2	308..329	CDD:316026	9/20 (45%)
		C2H2 Zn finger	321..341	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050