DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and prz1

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_593073.1	Gene:	prz1 / 2541806	PomBaseID:	SPAC4G8.13c	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	413	Identity:	94/413 - (22%)
Similarity:	133/413 - (32%)	Gaps:	120/413 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DVLSNILKLTGFWLRNQPGVPTRICLSCLL------DLNDAIAFRERCIRTNSSWFEKQGKQEDS 83
            |:||| .....|...|.|........|..|      .||...| ||..||:.:|.|    .::.:
pombe   319 DLLSN-HSTPSFIFENSPSAEFSHQSSPYLVPNSGRTLNSENA-RESTIRSVNSPF----SEDHA 377

  Fly    84 DTETAREGGNNRLESRV--DVMPISIAQPQRRRILPQRSKKVDGVPLKTVETPIYPLVVPEIPPA 146
            |..         |.:.|  .:.|.:::    ..:|...|....|.|...        |||..|..
pombe   378 DAS---------LTTHVFDPISPTALS----NSVLNYDSNNFSGTPQIN--------VVPSSPSK 421

  Fly   147 DLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPRTLQ-------VIGEVQKN 204
            ....|       .:.:.|.|.:|..:.......|.|..| .|.|....||       .:......
pombe   422 SQSGP-------SLPANPLLQTDISITYSQSASPVSGQP-AMNENSYDLQNANLCAPEMSPTYTA 478

  Fly   205 RRKPRSKG---------------------CLEECPGKD-MAKIENIDSTTNKTKEEKYATRNKWG 247
            |.:..|.|                     ||......: :.||||.:|.:|    :..:.||
pombe   479 RHRSNSAGSRFDAYEPIPQLYTHFSHSSECLSVNQDTELLGKIENDNSKSN----DYLSVRN--- 536

  Fly   248 AAKRAYALEHRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHR 312
            ...|:.:|.             |..||.:.:....|...|                     .|.:
pombe   537 TRPRSRSLN-------------SLVGNKSENSSSSKAKSE---------------------SKSQ 567

  Fly   313 GELPYVCKY--CGKRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQP 375
            |.  |||.:  |.|||.......:|...|..   :||..||.|:|:|......:.|..:|||.:.
pombe   568 GN--YVCTFAGCNKRFTRAYNLKSHMNTHTN---YRPFQCSICKKSFARQHDKRRHEQLHTGIKA 627

  Fly   376 FHCELCQTFFNRRNALATHYKSK 398
            |.|..|...|.|.:||..||||:
pombe   628 FACVTCNQRFARMDALNRHYKSE 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	18/56 (32%)
		zf-C2H2	260..282	CDD:278523	3/21 (14%)
		C2H2 Zn finger	262..282	CDD:275368	3/19 (16%)
		C2H2 Zn finger	290..311	CDD:275368	0/20 (0%)
		COG5048	<298..>383	CDD:227381	25/86 (29%)
		C2H2 Zn finger	319..339	CDD:275368	6/21 (29%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		ZnF_U1	375..407	CDD:197732	11/24 (46%)
		C2H2 Zn finger	378..396	CDD:275368	7/17 (41%)
prz1	NP_593073.1	COG5048	121..620	CDD:227381	80/381 (21%)
		zf-C2H2	570..594	CDD:278523	8/23 (35%)
		C2H2 Zn finger	577..594	CDD:275368	5/16 (31%)
		zf-H2C2_2	586..611	CDD:290200	9/27 (33%)
		C2H2 Zn finger	602..622	CDD:275368	6/19 (32%)
		zf-H2C2_2	616..639	CDD:290200	8/22 (36%)
		C2H2 Zn finger	630..648	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100