DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17806 and ZNF620

DIOPT Version :9

Sequence 1:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_016861553.1	Gene:	ZNF620 / 253639	HGNCID:	28742	Length:	467	Species:	Homo sapiens

Alignment Length:	345	Identity:	86/345 - (24%)
Similarity:	133/345 - (38%)	Gaps:	82/345 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 PLVVPEIPPADLVDPLRCEDPIQVKSEPQLSSDYP-VESMNHEEPASEMPQVMKEEPRTLQVIGE 200
            |::|.::...:|...|   ||.:......|....| .|:...:|..:....|.||......::|.
Human   102 PVLVSQLEQGELPWGL---DPWEPMGREALRGICPGDEARTEKEGLTPKDHVSKETESFRLMVGG 163

  Fly   201 VQKNRRKPRSKG-CLEECPG----KDMAKIENIDSTTNKTKEEKYATRN--KWGAAKRAYALEHR 258
            :..|..:....| .||:..|    |..:|..:...|:.: ..|.|..:|  |:....:..::..:
Human   164 LPGNVSQHLDFGSSLEQPQGHWIIKTKSKRRHFTDTSAR-HHEAYEVKNGEKFEKLGKNISVSTQ 227

  Fly   259 L------------YFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDR-MEFTQHLLN------ 304
            |            |.|.|||:.|.:..:|:.|.:.|.|.|.|:|:||.: ..:...|:.
Human   228 LTTNQTNPSGQISYECGQCGRYFIQMADFHRHEKCHTGEKSFECKECGKYFRYNSLLIRHQIIHT 292

  Fly   305 ---------------------LHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNH--------- 339
                                 .|.|| |.||.||.||.|||.|.:....|.|:|.|
Human   293 GKKPFKCKECGKGLSSDTALIQHQRI-HTGEKPYECKECGKAFSSSSVFLQHQRFHTGEKLYECN 356

  Fly   340 ---------KESPVH-------RPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRR 388
                     ....||       :|:.|..|.|...::|||..|..:||||:||.|:.|...||::
Human   357 ECWKTFSCSSSFTVHQRMHTGEKPYECKECGKRLSSNTALTQHQRIHTGEKPFECKECGKAFNQK 421

  Fly   389 NALATHYK----SKHHRLKV 404
            ..|..|.:    .|.:..||
Human   422 ITLIQHQRVHTGEKPYECKV 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071
		zf-C2H2	260..282	CDD:278523	8/21 (38%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	7/48 (15%)
		COG5048	<298..>383	CDD:227381	37/136 (27%)
		C2H2 Zn finger	319..339	CDD:275368	9/19 (47%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		ZnF_U1	375..407	CDD:197732	11/34 (32%)
		C2H2 Zn finger	378..396	CDD:275368	6/17 (35%)
ZNF620	XP_016861553.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050