DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17806 and ZNF485

DIOPT Version :9

Sequence 1:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001305069.1 Gene:ZNF485 / 220992 HGNCID:23440 Length:441 Species:Homo sapiens


Alignment Length:282 Identity:80/282 - (28%)
Similarity:112/282 - (39%) Gaps:56/282 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 SSDYPVESMNHEEPASEMPQVMKE------EPRTLQVIGEVQKNRRKPRSKGCLEECPGKDMAK- 224
            :|.:.....||   .||.|...||      ...:|....:|...::..|   |: || ||.:.| 
Human   142 NSSFISHQRNH---TSEKPHKCKECGIAFMNSSSLLNHHKVHAGKQPYR---CI-EC-GKFLKKH 198

  Fly   225 --IENIDSTTNKTKEEKYATRNKWGAAKRAYALEH-------RLYFCDQCGKTFSEKGNFNVHLR 280
              ..|.....::.|..|.....| ...|.:..|.|       :.|.|:.|||.|::......|.|
Human   199 STFINHQRIHSREKPHKCIECGK-TFRKNSILLSHQRIHTGQKPYKCNDCGKAFAQNAALTRHER 262

  Fly   281 RHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNHK-ESPV 344
            .|.|.|.|:|.:|.|.......:..|.:| |.||.||.|..|||.|......::|:|.|. |.|.
Human   263 IHSGEKPFKCNKCGRAFRDNSTVLEHQKI-HTGEKPYQCNECGKAFRKSSTLISHQRMHTGEKPY 326

  Fly   345 H------------------------RPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFF 385
            |                        :|:.|..|.|||..|:.|..|..:||||:|:||:.|...|
Human   327 HCSKCGKSFRYSSSFAGHQKTHSGNKPYQCRDCGKAFTKSSTLTGHQRIHTGEKPYHCKKCGKAF 391

  Fly   386 NRRNALATHYKSKHHRLKVEEQ 407
            ...:.|.     :|.||...|:
Human   392 RHSSGLV-----EHQRLHTGEK 408

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 8/21 (38%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
C2H2 Zn finger 290..311 CDD:275368 5/20 (25%)
COG5048 <298..>383 CDD:227381 35/109 (32%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
ZnF_U1 375..407 CDD:197732 9/31 (29%)
C2H2 Zn finger 378..396 CDD:275368 4/17 (24%)
ZNF485NP_001305069.1 KRAB 11..71 CDD:214630
KRAB 11..50 CDD:279668
COG5048 <124..361 CDD:227381 60/228 (26%)
C2H2 Zn finger 132..152 CDD:275368 1/9 (11%)
C2H2 Zn finger 160..180 CDD:275368 3/19 (16%)
C2H2 Zn finger 188..208 CDD:275368 7/21 (33%)
C2H2 Zn finger 216..236 CDD:275368 4/20 (20%)
zf-H2C2_2 229..253 CDD:290200 8/23 (35%)
C2H2 Zn finger 244..264 CDD:275368 7/19 (37%)
zf-H2C2_2 256..279 CDD:290200 9/22 (41%)
C2H2 Zn finger 272..292 CDD:275368 5/20 (25%)
zf-H2C2_2 287..307 CDD:290200 11/20 (55%)
C2H2 Zn finger 300..320 CDD:275368 7/19 (37%)
zf-H2C2_2 313..337 CDD:290200 6/23 (26%)
C2H2 Zn finger 328..348 CDD:275368 0/19 (0%)
C2H2 Zn finger 356..376 CDD:275368 8/19 (42%)
zf-H2C2_2 372..393 CDD:290200 10/20 (50%)
C2H2 Zn finger 384..404 CDD:275368 6/24 (25%)
zf-H2C2_2 397..419 CDD:290200 5/17 (29%)
C2H2 Zn finger 412..432 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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