Protein Alignment CG17803 and ZNF347

DIOPT Version :10

• Sequence 1: NP_650657.2
• Gene: CG17803 / 42141
• FlyBaseID: FBgn0038547
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001166145.1
• Gene: ZNF347 / 84671
• HGNCID: 16447
• Length: 840
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 127/538 - (23%)
• Similarity: 193/538 - (35%)
• Gaps: 143/538 - (26%)

  Fly    85 KCRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVWIQQGVKELPHHICSTCQE--TVNKSM-- 145
            ||..|.::.||           |..|..|.|:.||        |.|:. |:.|.:  |.|..:
Human   319 KCNECGKVFSR-----------NSQLSQHQKIHTG--------EKPYK-CNECGKVFTQNSHLVR 363

  Fly   146 -------EFRAKCQQVDKKLR--------QTT---EK-YNIQICDE--EMESELENVLYEESAQQ 189
                   |...||.:..|..|        |.|   || |....|.:  ...|.|.|
Human   364 HRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECGKVFTQNSHLTN--------- 419

  Fly   190 AKGVVGLEDFSSELLPDSEGVLDEDDFPLDAEPTQFSLSEDELDLDRDTEKDFALEQNKSCNEII 254
                                     .:.:......:..:|        ..|.|.:..:.:.:.:|
Human   420 -------------------------HWRIHTGEKPYKCNE--------CGKAFGVRSSLAIHLVI 451

  Fly   255 SI----RKCKTKEEIGKV----DHGAKVYKVVLGE-----------YNSLKETAPKYSLSLPKKP 300
            ..    .||   .|.|||    .|.|:...:..||           :.:.........:...:||
Human   452 HTGEKPYKC---HECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKP 513

  Fly   301 QL-----RVSPEEKNRRRRERIQAKPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKK 360
            ..     :|..:..:....:||......|:|::||..|...|.|..|.:.|...|.::|.||.|
Human   514 YKCNECGKVFTQNSHLANHQRIHTGVKPYMCNECGKAFSVYSSLTTHQVIHTGEKPYKCNECGK- 577

  Fly   361 FYDLYTRNIHV---RALHKGEHPFPCNHCNESFANASSRHRHERDVHGAGNRIRTRVKSK----- 417
               ::|:|.|:   |.:|.||.|:.||.|.:.|.:.|...||:| :|......:.....|
Human   578 ---VFTQNSHLARHRGIHTGEKPYKCNECGKVFRHNSYLSRHQR-IHTGEKPYKYNEYGKAFSEH 638

  Fly   418 ---------EEGSSRHYCTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQAL 473
                     ..|...:.|.:|.|.:|....|..|...|.|.:|:||..|...|:..|.:.|||.:
Human   639 SNLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARHQRV 703

  Fly   474 H-DKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICDVHYRHRYNLNKHKNTDLHRDNMQK 537
            | .:.|..|:.|.|.|.:||.||.||.:|||..|::|..|...:....:|.:|:.  :|..  :|
Human   704 HTGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNSHLARHRG--IHTG--EK 764

  Fly   538 AIKEEVNGLQQAFKDIDK 555
            ..|  .|...:||....|
Human   765 PYK--CNECGKAFSQTSK 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_650657.2	zf-AD	86..160	CDD:214871	21/92 (23%)
		SUF4-like	320..>376	CDD:411020	18/58 (31%)
		C2H2 Zn finger	323..351	CDD:411020	9/27 (33%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..375	CDD:411020	8/23 (35%)
		C2H2 Zn finger	354..375	CDD:275368	8/23 (35%)
		C2H2 Zn finger	383..401	CDD:275368	7/17 (41%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		C2H2 Zn finger	454..474	CDD:275368	7/19 (37%)
		C2H2 Zn finger	481..501	CDD:275368	10/19 (53%)
		C2H2 Zn finger	509..528	CDD:275368	4/18 (22%)
ZNF347	NP_001166145.1	KRAB	8..67	CDD:214630
		C2H2 Zn finger	265..284	CDD:275368
		COG5048	273..728	CDD:227381	110/478 (23%)
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368	8/30 (27%)
		C2H2 Zn finger	348..368	CDD:275368	4/19 (21%)
		C2H2 Zn finger	376..396	CDD:275368	4/19 (21%)
		C2H2 Zn finger	404..424	CDD:275368	4/53 (8%)
		C2H2 Zn finger	432..452	CDD:275368	3/27 (11%)
		C2H2 Zn finger	460..480	CDD:275368	7/22 (32%)
		C2H2 Zn finger	488..508	CDD:275368	0/19 (0%)
		C2H2 Zn finger	516..536	CDD:275368	2/19 (11%)
		C2H2 Zn finger	544..564	CDD:275368	7/19 (37%)
		C2H2 Zn finger	572..592	CDD:275368	8/23 (35%)
		C2H2 Zn finger	600..620	CDD:275368	8/20 (40%)
		C2H2 Zn finger	628..648	CDD:275368	1/19 (5%)
		C2H2 Zn finger	656..676	CDD:275368	6/19 (32%)
		C2H2 Zn finger	684..704	CDD:275368	7/19 (37%)
		C2H2 Zn finger	712..732	CDD:275368	10/19 (53%)
		COG5048	723..>817	CDD:227381	20/64 (31%)
		C2H2 Zn finger	740..760	CDD:275368	4/21 (19%)
		C2H2 Zn finger	768..788	CDD:275368	4/13 (31%)
		C2H2 Zn finger	795..813	CDD:275368