Protein Alignment CG17803 and ZNF665

DIOPT Version :10

• Sequence 1: NP_650657.2
• Gene: CG17803 / 42141
• FlyBaseID: FBgn0038547
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001340387.1
• Gene: ZNF665 / 79788
• HGNCID: 25885
• Length: 706
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 101/418 - (24%)
• Similarity: 163/418 - (38%)
• Gaps: 102/418 - (24%)

  Fly   136 TCQETVNK---------------SMEFRAKCQQVD----KKLRQTTEKYNIQICDEEMES-ELEN 180
            ||.:...|               |::...||...|    .|.......|.:::  |.:|| :...
Human    51 TCLDPAQKTLYRDVMLENYRNLVSLDISCKCVNTDLPPKGKNNMGEAFYTVKL--ERLESCDTVG 113

  Fly   181 VLYEESAQQAKGVVGLEDFSSELLPDSEG------VLDEDDFPLDAEPTQFSLSEDELDLDRDTE 239
            :.::|..:..      .||..: ..|.||      :|.:::.|                 .|..:
Human   114 LSFQEVQKNT------YDFECQ-WKDDEGNYKTVLMLQKENLP-----------------GRRAQ 154

  Fly   240 KDFALEQNKSCNEIISIRKCKTKEEIGKVDHGAKVYKVVLGEYNSLKETAPKYSLSLPKKPQLRV 304
            :|.....|:.....:.:.......|:.:..|..|:|     |||                 |:..
Human   155 RDRRAAGNRHIENQLGVSFQSHLPELQQFQHEGKIY-----EYN-----------------QVEK 197

  Fly   305 SPEEKNRRRRERIQAKPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRNI 369
            ||..:.:           :|.||:||..|.|.|:|..|...|...|.::|.:|.|.|.......|
Human   198 SPNNRGK-----------HYKCDECGKVFSQNSRLTSHKRIHTGEKPYQCNKCGKAFTVRSNLTI 251

  Fly   370 HVRALHKGEHPFPCNHCNESFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSRHYCTQCTKSYT 434
            | :.:|.||.|:.||.|.:.|:..|:...|:| :|              .|...:.|.:|.|::.
Human   252 H-QVIHTGEKPYKCNECGKVFSQPSNLAGHQR-IH--------------TGEKPYKCNECGKAFR 300

  Fly   435 SKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQALH-DKFPIRCDICLKGFLLRSQLTKHQ 498
            :...|..|...|.|.:|::||.|...|...|.:..|:.:| .:.|.:|:.|.|.|.:||.||.||
Human   301 AHSKLTTHQVIHTGEKPYKCKECGKCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVRSSLTTHQ 365

  Fly   499 DVHTGMHPHRCEICDVHYRHRYNLNKHK 526
            .:|||..|::|..|...:||...|.||:
Human   366 TIHTGEKPYKCNECGKVFRHNSYLAKHR 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_650657.2	zf-AD	86..160	CDD:214871	8/42 (19%)
		SUF4-like	320..>376	CDD:411020	18/55 (33%)
		C2H2 Zn finger	323..351	CDD:411020	11/27 (41%)
		C2H2 Zn finger	326..346	CDD:275368	9/19 (47%)
		C2H2 Zn finger	354..375	CDD:411020	6/20 (30%)
		C2H2 Zn finger	354..375	CDD:275368	6/20 (30%)
		C2H2 Zn finger	383..401	CDD:275368	6/17 (35%)
		C2H2 Zn finger	426..446	CDD:275368	5/19 (26%)
		C2H2 Zn finger	454..474	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368	10/19 (53%)
		C2H2 Zn finger	509..528	CDD:275368	7/18 (39%)
ZNF665	NP_001340387.1	KRAB	37..76	CDD:460171	4/24 (17%)
		COG5048	192..580	CDD:227381	73/246 (30%)
		C2H2 Zn finger	208..228	CDD:275368	9/19 (47%)
		C2H2 Zn finger	236..256	CDD:275368	6/20 (30%)
		C2H2 Zn finger	264..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..312	CDD:275368	5/19 (26%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		C2H2 Zn finger	348..368	CDD:275368	10/19 (53%)
		C2H2 Zn finger	376..396	CDD:275368	7/18 (39%)
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		zf-H2C2_2	584..608	CDD:463886
		C2H2 Zn finger	600..620	CDD:275368
		zf-H2C2_2	612..637	CDD:463886
		C2H2 Zn finger	628..648	CDD:275368
		zf-H2C2_2	640..664	CDD:463886
		C2H2 Zn finger	656..676	CDD:275368
		zf-H2C2_2	669..693	CDD:463886
		C2H2 Zn finger	684..704	CDD:275368