Protein Alignment CG17803 and ZNF99

DIOPT Version :10

• Sequence 1: NP_650657.2
• Gene: CG17803 / 42141
• FlyBaseID: FBgn0038547
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001073878.2
• Gene: ZNF99 / 7652
• HGNCID: 13175
• Length: 864
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 111/494 - (22%)
• Similarity: 191/494 - (38%)
• Gaps: 117/494 - (23%)

  Fly    73 TGLQECDPPPASKCRTCFRI------ISRH------------EDAQDLYDRVNIALLHHIKVITG 119
            ||.:.|      ||..|.::      :.:|            |:....: :.:..|..|..:.||
Human   252 TGKKPC------KCEECGKVFNNSSTLMKHKIIHTGKKPYKCEECGKAF-KQSSHLTRHKAIHTG 309

  Fly   120 VWIQQGVKELPHHICSTCQETVNKSMEFRA-----------KCQQVDKKLRQ--TTEKYNIQICD 171
                    |.|:. |..|.:..|.....|.           ||::..|...|  |..|:.|
Human   310 --------EKPYK-CEECGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQSSTLRKHEI---- 361

  Fly   172 EEMESELENVLYEESAQQAKGVVGLEDFSSELLPDSEGVLDEDDFPLDAEPTQFSLSEDELDLDR 236
              :.:|.:...|||..:....:..|.         ...::.....|...|
Human   362 --IHTEEKPYKYEECGKAFSNLSALR---------KHEIIHTGQKPYKCE--------------- 400

  Fly   237 DTEKDFALEQNKSCNEIISIRKCKTKEEIGKVDHGAKVYKVVLGEYNSLKETAPKYSLSLPKKPQ 301
            :..|.|......:.:::|     .|.|:..|.:...|.:|    .:::|::....::...|.|
Human   401 ECGKAFKWSSKLTVHKVI-----HTAEKPCKCEECGKAFK----RFSALRKHKIIHTGKQPYK-- 454

  Fly   302 LRVSPEEKNR--------RRRERIQAKPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECP 358
                .||.::        |:.|.|......|.|::||..|:..|:|.:|.:.|...|..:|.||.
Human   455 ----CEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCEECG 515

  Fly   359 KKFYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSR 423
            |.|........| :.:|.|:.|:.|..|.::|.|:|:..:| :.:|              .|...
Human   516 KAFKHFSALRKH-KIIHTGKKPYKCEECGKAFNNSSTLMKH-KIIH--------------TGKKP 564

  Fly   424 HYCTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQALH-DKFPIRCDICLKG 487
            :.|.:|.|::.....|..|...|.|.:|::|:.|...|...||:::||.:| .|.|.:|:.|.|.
Human   565 YKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEECGKA 629

  Fly   488 FLLRSQLTKHQDVHTGMHPHRCEICDVHYRHRYNLNKHK 526
            |...|.|.||:.:|||..|::||.|...::...:|.:||
Human   630 FSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSHLTRHK 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_650657.2	zf-AD	86..160	CDD:214871	17/102 (17%)
		SUF4-like	320..>376	CDD:411020	16/55 (29%)
		C2H2 Zn finger	323..351	CDD:411020	9/27 (33%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..375	CDD:411020	6/20 (30%)
		C2H2 Zn finger	354..375	CDD:275368	6/20 (30%)
		C2H2 Zn finger	383..401	CDD:275368	6/17 (35%)
		C2H2 Zn finger	426..446	CDD:275368	5/19 (26%)
		C2H2 Zn finger	454..474	CDD:275368	7/19 (37%)
		C2H2 Zn finger	481..501	CDD:275368	8/19 (42%)
		C2H2 Zn finger	509..528	CDD:275368	6/18 (33%)
ZNF99	NP_001073878.2	KRAB	4..64	CDD:214630
		C2H2 Zn finger	147..167	CDD:275368
		C2H2 Zn finger	175..195	CDD:275368
		C2H2 Zn finger	203..223	CDD:275368
		C2H2 Zn finger	232..251	CDD:275368
		C2H2 Zn finger	259..279	CDD:275368	3/19 (16%)
		COG5048	267..684	CDD:227381	105/473 (22%)
		C2H2 Zn finger	287..307	CDD:275368	3/20 (15%)
		C2H2 Zn finger	315..335	CDD:275368	4/19 (21%)
		C2H2 Zn finger	343..363	CDD:275368	6/25 (24%)
		C2H2 Zn finger	371..391	CDD:275368	4/28 (14%)
		C2H2 Zn finger	399..419	CDD:275368	4/39 (10%)
		C2H2 Zn finger	427..447	CDD:275368	3/23 (13%)
		C2H2 Zn finger	455..475	CDD:275368	4/19 (21%)
		C2H2 Zn finger	483..503	CDD:275368	7/19 (37%)
		C2H2 Zn finger	511..531	CDD:275368	6/20 (30%)
		COG5048	534..857	CDD:227381	45/150 (30%)
		C2H2 Zn finger	539..559	CDD:275368	6/20 (30%)
		C2H2 Zn finger	567..587	CDD:275368	5/19 (26%)
		C2H2 Zn finger	595..615	CDD:275368	7/19 (37%)
		C2H2 Zn finger	623..643	CDD:275368	8/19 (42%)
		C2H2 Zn finger	651..671	CDD:275368	6/18 (33%)
		C2H2 Zn finger	679..699	CDD:275368
		C2H2 Zn finger	707..727	CDD:275368
		C2H2 Zn finger	735..755	CDD:275368
		C2H2 Zn finger	763..783	CDD:275368
		C2H2 Zn finger	791..811	CDD:275368
		C2H2 Zn finger	819..839	CDD:275368