Protein Alignment CG17803 and ZNF878

DIOPT Version :10

• Sequence 1: NP_650657.2
• Gene: CG17803 / 42141
• FlyBaseID: FBgn0038547
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_016882684.1
• Gene: ZNF878 / 729747
• HGNCID: 37246
• Length: 567
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 123/564 - (21%)
• Similarity: 192/564 - (34%)
• Gaps: 155/564 - (27%)

  Fly    60 DSAFFDS---DFEEESTGLQECDPPPASKCRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVW 121
            ||..|:.   :|.:|...|.:    |:.|               :||..|....|.::..|...|
Human    38 DSVAFEDVAVNFTQEEWALLD----PSQK---------------NLYREVMQETLRNLTSIGKKW 83

  Fly   122 IQQGVKELPHHICSTCQETVNKSMEFRAKCQQVDKKLRQTTEKYN-----IQICDEEMESELENV 181
            ..|.:::          |..|.....|   :.:.::|.::.|.:.     .|:.|:.::.:...|
Human    84 NNQYIED----------EHQNPRRNLR---RLIGERLSESKESHQHGEVLTQVPDDTLKKKTPGV 135

  Fly   182 LYEESAQQAKGVVGLEDFSSELLPDSEGVLDEDDFPLDAEPTQFSLSEDELDLDRDTEKDFALEQ 246
            ...||:...:..:||...:..|                   ..||.|..
Human   136 QSYESSVCGEIGIGLSSLNRHL-------------------RAFSYSSS---------------- 165

  Fly   247 NKSCNEIISIRKCKTKEEIGKVDHGAKVYKVVLGEYNSLKETAPKYSLSLPKKPQLRVSPEEKNR 311
                   ::|.        |:...|.|.|:        .||....:..             ..:.
Human   166 -------LAIH--------GRTHTGEKPYE--------CKECGKAFRF-------------PSSV 194

  Fly   312 RRRERIQAKPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRNIHVRALHK 376
            ||.|||.:....|.|.:||..|...|.::.|...|:..|.:||.:|.|....|.:...|:| :|.
Human   195 RRHERIHSAKKPYECKQCGKAFSFPSSVRRHERIHSAKKPYECKQCGKALSYLVSFQTHMR-MHT 258

  Fly   377 GEHPFPCNHCNESFANASSRHRHERDVHGAGNRIRTRVKSK--------------EEGSSRHYCT 427
            ||.|..||.|.::|.:.||..|||:. |....|.:.:...|              ..|...:.||
Human   259 GERPHKCNICGKAFFSPSSLKRHEKS-HTGEKRYKCKQCDKAFNCPSSFQYHERTHSGEKPYECT 322

  Fly   428 QCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQALH-DKFPIRCDICLKGFLLR 491
            ||.|::.|.|.|.:|...|.|.:|::||:|...|...::.:.|:..| .:.|..|..|:|.|...
Human   323 QCRKAFRSVKYLRVHERKHTGEKPYECKLCGKGFISSTSFRYHEKTHTGEKPYECKKCVKAFSFV 387

  Fly   492 SQLTKHQDVHTGMHPHRCEIC--------DVHYRHR-------YNLNKHKNTDLHRDNMQKAIKE 541
            ..|..|:..|||..|..|:.|        ..||..|       |...:..........:||.|:.
Human   388 KDLRIHERTHTGEKPFECKQCGKTFTSSNSFHYHERTHTGEKPYECKQCGKAFRSASVLQKHIRT 452

  Fly   542 EVNGLQQAFKDIDKEMDFESQTPMQPNAQEVRARTQDEKTQTIE 585
            .........|...|.....||..|.            |:|.|.|
Human   453 HTGEKPYGCKQCGKVFRVASQLKMH------------ERTHTGE 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_650657.2	zf-AD	86..160	CDD:214871	11/73 (15%)
		SUF4-like	320..>376	CDD:411020	16/55 (29%)
		C2H2 Zn finger	323..351	CDD:411020	8/27 (30%)
		C2H2 Zn finger	326..346	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..375	CDD:411020	6/20 (30%)
		C2H2 Zn finger	354..375	CDD:275368	6/20 (30%)
		C2H2 Zn finger	383..401	CDD:275368	8/17 (47%)
		C2H2 Zn finger	426..446	CDD:275368	9/19 (47%)
		C2H2 Zn finger	454..474	CDD:275368	5/19 (26%)
		C2H2 Zn finger	481..501	CDD:275368	6/19 (32%)
		C2H2 Zn finger	509..528	CDD:275368	6/33 (18%)
ZNF878	XP_016882684.1	KRAB	39..80	CDD:460171	11/59 (19%)
		COG5048	158..557	CDD:227381	95/393 (24%)
		C2H2 Zn finger	181..201	CDD:275368	6/32 (19%)
		C2H2 Zn finger	209..229	CDD:275368	6/19 (32%)
		C2H2 Zn finger	237..257	CDD:275368	6/20 (30%)
		C2H2 Zn finger	265..285	CDD:275368	9/20 (45%)
		C2H2 Zn finger	293..313	CDD:275368	1/19 (5%)
		C2H2 Zn finger	321..341	CDD:275368	9/19 (47%)
		C2H2 Zn finger	349..369	CDD:275368	5/19 (26%)
		C2H2 Zn finger	377..397	CDD:275368	6/19 (32%)
		C2H2 Zn finger	405..425	CDD:275368	5/19 (26%)
		C2H2 Zn finger	433..453	CDD:275368	3/19 (16%)
		C2H2 Zn finger	461..481	CDD:275368	6/31 (19%)
		C2H2 Zn finger	489..509	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368