DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and CG18764

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	119/434 - (27%)
Similarity:	194/434 - (44%)	Gaps:	80/434 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 ASKCRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVWIQQGVKELPHHICSTCQETVNKSMEF 147
            |.:||||..|| .::..::|:...|..:|..|.::||..:... .|||..||:.|...:|:::.|
  Fly     2 ALQCRTCGSII-YNKMPKNLFHIENEKMLQDINLVTGTTLHND-PELPSSICACCTLDLNQAILF 64

  Fly   148 RAKCQQVDKKL---RQTTEKYNIQICDEEMES----------ELENVLYEESAQQAKGVVGLEDF 199
            |.:|....|:|   |::.|........|||.|          |::..:.|...:       :.|.
  Fly    65 RERCILTQKQLVHRRRSPEAKEPAEDVEEMASPPDCLNDPFGEVDEYIVESPEE-------VLDH 122

  Fly   200 SSELLPDSEGVLDEDDFPLDAEPTQFSLSEDELDLDRDTEKDFALEQNKSCNEII-SIRK----- 258
            .|    |:...||||:: :|        |.:::|..:|. .:.|.|.::....:| |::|
  Fly   123 DS----DAHHDLDEDNY-ID--------SVEDVDALQDM-AEVAEEDSQDVESLISSVQKELESI 173

  Fly   259 CKTKEEIGKVDH----GAKVYKVVLGEY-------------NSLKETAPKYSLSLPKKPQLRV-- 304
            |.........|:    ....:...:.||             .|....:.|.:.:.||:.:..|
  Fly   174 CNDDSNSDNNDYMEPQNGSYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTW 238

  Fly   305 -SPEEKNRRRRERIQAKPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRN 368
             :..|:....|:|:|.| ...||::||..|..:|..::|:|||...|||.|.:|.|:||..:...
  Fly   239 KNMTEEQIIERKRLQRK-RECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMT 302

  Fly   369 IHVRALHKGEHPFPCNHCNESFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSRHYCTQCTKSY 433
            :|.|.:|:||.|:.|..|.:||.|:::|..||          ||...:|.  .|.|:|.:|.||.
  Fly   303 LHQRIIHQGEKPYDCRFCTKSFHNSNTRLIHE----------RTHTNAKP--YSCHHCDKCFKSA 355

  Fly   434 TSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQALHDKF 477
            :.:|   .|...|.|.|.|.|.||:..|...:.:|.|  |..||
  Fly   356 SGRK---RHELIHTGVRAFACTICKQSFQRNTHLKAH--LRSKF 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871	24/76 (32%)
		COG5048	<323..528	CDD:227381	56/155 (36%)
		zf-C2H2	324..346	CDD:278523	8/21 (38%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..375	CDD:275368	7/20 (35%)
		C2H2 Zn finger	383..401	CDD:275368	7/17 (41%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		C2H2 Zn finger	454..474	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368
		C2H2 Zn finger	509..528	CDD:275368
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	23/72 (32%)
		C2H2 Zn finger	260..280	CDD:275368	7/19 (37%)
		zf-H2C2_2	272..297	CDD:290200	11/24 (46%)
		C2H2 Zn finger	288..309	CDD:275368	7/20 (35%)
		C2H2 Zn finger	317..337	CDD:275368	9/29 (31%)
		C2H2 Zn finger	345..365	CDD:275368	7/22 (32%)
		C2H2 Zn finger	373..391	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8018
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960