DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and znf1041

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001107903.1	Gene:	znf1041 / 565096	ZFINID:	ZDB-GENE-080213-11	Length:	443	Species:	Danio rerio

Alignment Length:	368	Identity:	93/368 - (25%)
Similarity:	142/368 - (38%)	Gaps:	70/368 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 DSEGVLDEDDFPLDAEPTQFSLSEDELDLDRDTEKDFALEQNKSCNEIISIRKCKTKEEIGKVDH 270
            :||.|..|:.|.:..|           ||...|:.....|:....||:....:..|.:|
Zfish     7 ESEDVKIEETFTVKEE-----------DLQEQTDPIVLKEETHQWNEMEEKHQDMTTDE------ 54

  Fly   271 GAKVYKVVLGEYNSLKETAPKYSLSLPKKPQLRVSPEEKNRRR------------RERIQAKPLN 323
                 |..|.|..|        |...|:|.:.|.:...|..|:            |...:.||.|
Zfish    55 -----KPTLTEKTS--------SQGRPRKSKSRCNVSCKQSRKSFSQKPNLDVHMRVHTREKPYN 106

  Fly   324 YVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNE 388
              |::||.:|.|:...::|:..|...:.:.|.:|.:.||......:| |.:|.||.|:.|..|.:
Zfish   107 --CEQCGKSFGQKQSFKIHMRIHTGERPYTCQQCGQSFYHAGNFAVH-RRIHTGERPYTCQQCGQ 168

  Fly   389 SFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSRHYCTQCTKSYTSKKGLVLHMNFHNGSRPFQ 453
            ||....:...|.| :|              .|...:.|.||.||:.....|.:||..|.|.||:.
Zfish   169 SFYTGGNLAVHMR-IH--------------TGEKPYSCIQCGKSFKQNGTLKVHMRSHTGERPYT 218

  Fly   454 CKICQMKFADPSAMKRHQALH-DKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICDVHYR 517
            |::|...|.......:|..:| .:.|..|..|.|.|...:.|..|..:|||..|:.|..|...::
Zfish   219 CQLCGKSFYTTGNFAQHMRIHTGERPYTCQQCGKSFYQSANLAAHMRIHTGEKPYSCPQCGKSFK 283

  Fly   518 HRYNLNKHKNTDLHRDNMQKAIKEEVNGLQQAFKDIDKEMDFE 560
            ...||..|..|    .|.:::|.     ..|..|...::.|.|
Zfish   284 QNSNLEAHIKT----HNRERSIT-----CTQCKKSFAQKQDLE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871
		COG5048	<323..528	CDD:227381	59/205 (29%)
		zf-C2H2	324..346	CDD:278523	6/21 (29%)
		C2H2 Zn finger	326..346	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..375	CDD:275368	6/20 (30%)
		C2H2 Zn finger	383..401	CDD:275368	5/17 (29%)
		C2H2 Zn finger	426..446	CDD:275368	8/19 (42%)
		C2H2 Zn finger	454..474	CDD:275368	4/19 (21%)
		C2H2 Zn finger	481..501	CDD:275368	6/19 (32%)
		C2H2 Zn finger	509..528	CDD:275368	5/18 (28%)
znf1041	NP_001107903.1	C2H2 Zn finger	79..99	CDD:275368	3/19 (16%)
		zf-H2C2_2	91..114	CDD:290200	7/24 (29%)
		COG5048	103..>429	CDD:227381	68/242 (28%)
		C2H2 Zn finger	107..127	CDD:275368	6/19 (32%)
		zf-H2C2_2	119..142	CDD:290200	4/22 (18%)
		C2H2 Zn finger	135..155	CDD:275368	6/20 (30%)
		C2H2 Zn finger	163..183	CDD:275368	6/20 (30%)
		zf-H2C2_2	175..200	CDD:290200	9/39 (23%)
		C2H2 Zn finger	191..211	CDD:275368	8/19 (42%)
		zf-H2C2_2	204..228	CDD:290200	10/23 (43%)
		C2H2 Zn finger	219..239	CDD:275368	4/19 (21%)
		zf-H2C2_2	231..254	CDD:290200	6/22 (27%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		zf-H2C2_2	259..284	CDD:290200	8/24 (33%)
		C2H2 Zn finger	275..295	CDD:275368	6/23 (26%)
		C2H2 Zn finger	303..323	CDD:275368	4/15 (27%)
		zf-H2C2_2	315..340	CDD:290200	2/3 (67%)
		C2H2 Zn finger	331..351	CDD:275368
		zf-H2C2_2	344..368	CDD:290200
		C2H2 Zn finger	359..379	CDD:275368
		C2H2 Zn finger	387..407	CDD:275368
		zf-H2C2_2	399..424	CDD:290200
		C2H2 Zn finger	415..435	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910