DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and znf995

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_017209820.1	Gene:	znf995 / 563697	ZFINID:	ZDB-GENE-080215-13	Length:	358	Species:	Danio rerio

Alignment Length:	368	Identity:	95/368 - (25%)
Similarity:	142/368 - (38%)	Gaps:	97/368 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 DSEGVLDEDDFPLDAEPTQFSLSEDELDLDRDTEKDFALEQNKSCNEIISIRKCKTKEEIGKVDH 270
            :||.|..|:.|.:..|           ||...|:.....|:....||:...::..|.:|
Zfish     7 ESEDVKIEETFTVKQE-----------DLQEQTDLMLLKEKTHQQNEMEEKQQDMTTDE------ 54

  Fly   271 GAKVYKVVLGEYNSLKETAPKYSLSLPKKPQLRVSPEEKNRRRRERIQAKP-LNYVCDKCGHTFR 334
                           |.|..|.:||                |.|.| ::|| .|:.|.:||.:|.
Zfish    55 ---------------KPTLTKKTLS----------------RGRPR-KSKPRCNFSCKQCGKSFS 87

  Fly   335 QRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRHRH 399
            |:.:|.:|:..|.|.|.:.|.:|.|.||:.....:|:| :|.||.|:.|..|.:||....:...|
Zfish    88 QKPKLDVHIRDHTREKAYTCKQCGKSFYNTRNLTVHMR-IHTGERPYTCQQCGKSFHKTGNLTVH 151

  Fly   400 ERDVHGAGNR------------------IRTRVKSKEE-------------------------GS 421
            .| :| .|.|                  :..|:.:.|:                         |.
Zfish   152 LR-IH-TGERPYTCQQCGKSFQTTGNLTVHMRIHTGEKPYSCPQCGKSYSQNSNLEVHMRTHNGG 214

  Fly   422 SRHYCTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQALH-DKFPIRCDICL 485
            ....||||.||:..|:.|.|||..|.|.:|:.|..|...|...|.:|.|..:| .:.|..|..|.
Zfish   215 RTFVCTQCGKSFVKKQNLDLHMRIHTGEKPYTCTECGKSFPYKSTLKHHMIVHTGEKPFACAQCG 279

  Fly   486 KGFLLRSQLTKHQDVHTGMHPHRCEICDVHYRHRYNLNKHKNT 528
            |.|...:.|..|.:.|||.....|::|.....|:|::..|..|
Zfish   280 KSFTCNANLRNHMNGHTGTIVFTCDLCGKSLTHKYSIKNHMKT 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871
		COG5048	<323..528	CDD:227381	70/248 (28%)
		zf-C2H2	324..346	CDD:278523	7/21 (33%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..375	CDD:275368	7/20 (35%)
		C2H2 Zn finger	383..401	CDD:275368	5/17 (29%)
		C2H2 Zn finger	426..446	CDD:275368	11/19 (58%)
		C2H2 Zn finger	454..474	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368	6/19 (32%)
		C2H2 Zn finger	509..528	CDD:275368	5/18 (28%)
znf995	XP_017209820.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910