DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and CG17802

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	116/436 - (26%)
Similarity:	207/436 - (47%)	Gaps:	74/436 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 KCRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVWIQQGVKELPHHICSTCQETVNKSMEFRA 149
            :||.|..:|.. ::..:::|. |..::..|.::||:|:....| :|.::||.|..::..::.||.
  Fly     4 QCRLCGDLIYT-QNPVNIFDE-NSKMVRQIALVTGLWLTDHSK-MPRNMCSCCLLSLKSAIAFRQ 65

  Fly   150 KCQQVDKKL---RQTTEKYN--------------IQICDEEMESELENVLYEESAQQAKGVVGLE 197
            .|.:.:.:|   |::.|..:              ::|.|.|:|.|   ||||.|....:|:....
  Fly    66 ACIKTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQE---VLYEVSYADNEGLEEDH 127

  Fly   198 DFSSELLPDSEGVLDEDDFPLDAEPTQFSLSEDELD--------LDRDTEKDFALEQNKSC---- 250
            |...:...:|| |.:..:|...|....||..:||.:        :|:.|..|.. |:::.|
  Fly   128 DLYKKEEEESE-VNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDG-EESQECEESQ 190

  Fly   251 -NEIISIRKCKTKEEIGKVDHGAKVYKVVLGE-------YNSLKETAPKYSLSLPKKPQ----LR 303
             :|..|.:..:.:||..:.|.  ::::...|:       .:.::.|:.:.:|...|||:    .|
  Fly   191 PDEEESQQNEEDEEESQEDDD--ELWQNEDGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKR 253

  Fly   304 VSPEEKN--------RRRRERIQAKPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKK 360
            .||:..:        ::|:..|..|.  ::||.||..|..:....:|:|||:..|.||||||.:|
  Fly   254 SSPKNDDTDFLKPAKKKRKTYISQKV--HICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQK 316

  Fly   361 FYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSRHY 425
            .::.|..|||:|..|:||.|:.|..|:|.|.:::.|.|||..||            :.:.:.:::
  Fly   317 EFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVH------------RNKKTPKNF 369

  Fly   426 -CTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRH 470
             |..|.|.|.|......|...|.|.|.|.|::|::.|...|.:|.|
  Fly   370 KCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871	19/76 (25%)
		COG5048	<323..528	CDD:227381	52/149 (35%)
		zf-C2H2	324..346	CDD:278523	7/21 (33%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..375	CDD:275368	10/20 (50%)
		C2H2 Zn finger	383..401	CDD:275368	7/17 (41%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		C2H2 Zn finger	454..474	CDD:275368	6/17 (35%)
		C2H2 Zn finger	481..501	CDD:275368
		C2H2 Zn finger	509..528	CDD:275368
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	18/72 (25%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	10/20 (50%)
		C2H2 Zn finger	339..360	CDD:275368	8/20 (40%)
		C2H2 Zn finger	371..388	CDD:275370	5/16 (31%)
		zf-met	398..421	CDD:289631	6/18 (33%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8018
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960