DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17803 and CG14711

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	116/466 - (24%)
Similarity:	178/466 - (38%)	Gaps:	116/466 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PPASKCRTCFRIISRHEDAQDLYD------RVNIALLHHIKVITGVWIQQGVKELPHHICSTCQE 139
            |....||.|.......|....|:|      |..:..:..:..|..|.:|    .:|..:|.:|.|
  Fly     2 PEYMLCRICLTEDINSEAMAPLFDDNDAQCRELVRKIEEVGSIKLVPLQ----NIPSMLCYSCVE 62

  Fly   140 TVNKSMEFRAKCQQVDKKLRQTTEKYNIQICDEEMESE---------LENV--LYEESAQQAKGV 193
            .:..:.:||..||:.::       .:...:...||:||         .:|:  :||.:.....||
  Fly    63 RLTSAHKFRELCQESER-------TFATNVVKAEMKSEPTDEVPHVVADNIEYIYESANDFIDGV 120

  Fly   194 ---VGLEDFSSELLPDSEGVLDEDDFPLDAEPTQFSLSEDELDLDRDTEKDFALEQNKSCNEIIS 255
               :|:|:...|.|.|..|   |.....:.......|.||:|.:...|:.|:  :..:.|.: ..
  Fly   121 EDDIGMENIMEEPLEDGVG---ETSQAYETSTVVDDLDEDDLLVPNSTDSDY--QPIERCRK-AK 179

  Fly   256 IRKCK-TKEEIGKVDHGAKVYKVVLGEYNSLKETAPKYSLSLPKKPQLRVSPEEKNRRRRERIQA 319
            :||.: ||...|: ..||.     .|...|..|..|      |.:...:.|||           .
  Fly   180 VRKTRMTKRGRGR-PRGAS-----SGHPRSFSEERP------PVQASFKSSPE-----------V 221

  Fly   320 KPLNYVCDKCGHTFRQRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPCN 384
            ...|.:|:.||:.:.:|:.|.:|:.||...|.|:|..|.|.|......|.|:| :|.||.||.|.
  Fly   222 SSTNIMCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSFAGPSELNRHIR-VHTGEKPFLCK 285

  Fly   385 HCNESFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSRHYCTQCTKSYTSKKGLVLHMNFHNGS 449
            :||.|||:.||..||||.                                           |...
  Fly   286 YCNRSFADRSSNIRHERT-------------------------------------------HTNE 307

  Fly   450 RPFQCKICQMKFADPSAMKRHQALH-DKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICD 513
            |||.|..|...|:..:.:|.|...| .:.|..|.:|.|.|..:.||    |.|.|...|:..:
  Fly   308 RPFTCSTCGKAFSYSNVLKNHMLTHTGEKPFLCRVCNKTFSRKHQL----DQHLGTMTHQQTV-- 366

  Fly   514 VHYRH----RY 520
            :|:::    ||
  Fly   367 IHHKNERTGRY 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871	18/79 (23%)
		COG5048	<323..528	CDD:227381	59/203 (29%)
		zf-C2H2	324..346	CDD:278523	6/21 (29%)
		C2H2 Zn finger	326..346	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..375	CDD:275368	7/20 (35%)
		C2H2 Zn finger	383..401	CDD:275368	10/17 (59%)
		C2H2 Zn finger	426..446	CDD:275368	0/19 (0%)
		C2H2 Zn finger	454..474	CDD:275368	5/19 (26%)
		C2H2 Zn finger	481..501	CDD:275368	7/19 (37%)
		C2H2 Zn finger	509..528	CDD:275368	3/16 (19%)
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	18/85 (21%)
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		zf-H2C2_2	240..264	CDD:290200	9/23 (39%)
		COG5048	249..>362	CDD:227381	46/160 (29%)
		C2H2 Zn finger	256..276	CDD:275368	7/20 (35%)
		zf-H2C2_2	268..292	CDD:290200	12/24 (50%)
		C2H2 Zn finger	284..304	CDD:275368	12/62 (19%)
		zf-H2C2_2	299..321	CDD:290200	11/64 (17%)
		C2H2 Zn finger	312..332	CDD:275368	5/19 (26%)
		zf-H2C2_2	325..349	CDD:290200	8/23 (35%)
		C2H2 Zn finger	340..362	CDD:275368	9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960