DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and ranshi

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	110/459 - (23%)
Similarity:	183/459 - (39%)	Gaps:	131/459 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 CRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVWIQQGVKELPHHICSTCQETVNKSMEFRAK 150
            ||||.: .:..|.:.:::::.|...|.|||::||. :.:....||:.:|::||..:.:::.||.:
  Fly     6 CRTCGK-RTNAERSLNIFEKRNQTTLEHIKLLTGA-VLKNCSTLPNRLCASCQTCLQQAISFRER 68

  Fly   151 CQQVDKKL--RQTTEKYNIQICDEEMESELENVLYEESAQQAKGVVGLEDFSSELLPD-SEGVLD 212
            |.:|.::|  .|..|.: ::||.|..:|.||    :|..:.....:.:|   .|.|.| :||.:.
  Fly    69 CLEVQRELLHSQDDEDF-LRICQESPKSVLE----QEELELDLAEISIE---VERLDDLNEGPIQ 125

  Fly   213 EDDFPLDAEPTQFSLSEDELDLDRD---TEKDFALEQNKSCNEIISIRKCKTKEEIGKVDHGAKV 274
            ...|.::....:..::|||.:.:.|   :|.|:.:.::.:        :...|:|:
  Fly   126 SSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDT--------EVDAKQEL--------- 173

  Fly   275 YKVVLGEYNSLKETAPKYSLSLPKKPQLRVSPEEKNRRRRERIQAKPLNYVCDKCGHTFRQRSQL 339
                            |.....|||.:.|.:|.:.||           .:.|::||:..:.|...
  Fly   174 ----------------KSDSENPKKRRNRRNPRDSNR-----------TFFCEECGNHIKDRISF 211

  Fly   340 QMHLLRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRHRHERDVH 404
            .:|..||...|.|.|..|..:|........|:|. |.||.||.|.||:.||::.|:|.:|||.
  Fly   212 ILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRK-HTGEKPFKCRHCSRSFSDYSTRLKHERT-- 273

  Fly   405 GAGNRIRTRVKSKEEGSSRHYCTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKR 469
                                                     |...|||.||.|...|.....:|.
  Fly   274 -----------------------------------------HTNERPFVCKECNNAFTTSYILKN 297

  Fly   470 HQALHDKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICDVHYRHRYNLNKHKNTDLHRDN 534
            |..                           ||||....||::||..:....:|..|..::.||.|
  Fly   298 HML---------------------------VHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRN 335

  Fly   535 MQKA 538
            ||||
  Fly   336 MQKA 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871	22/75 (29%)
		COG5048	<323..528	CDD:227381	49/204 (24%)
		zf-C2H2	324..346	CDD:278523	5/21 (24%)
		C2H2 Zn finger	326..346	CDD:275368	5/19 (26%)
		C2H2 Zn finger	354..375	CDD:275368	5/20 (25%)
		C2H2 Zn finger	383..401	CDD:275368	8/17 (47%)
		C2H2 Zn finger	426..446	CDD:275368	0/19 (0%)
		C2H2 Zn finger	454..474	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368	0/19 (0%)
		C2H2 Zn finger	509..528	CDD:275368	5/18 (28%)
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	21/72 (29%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	23/97 (24%)
		C2H2 Zn finger	226..246	CDD:275368	5/20 (25%)
		zf-H2C2_2	238..262	CDD:290200	11/24 (46%)
		C2H2 Zn finger	254..274	CDD:275368	10/62 (16%)
		zf-H2C2_2	269..291	CDD:290200	11/64 (17%)
		C2H2 Zn finger	282..302	CDD:275368	6/46 (13%)
		zf-H2C2_2	295..319	CDD:290200	10/50 (20%)
		C2H2 Zn finger	310..328	CDD:275368	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960