DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and klu-1

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_493611.2	Gene:	klu-1 / 173366	WormBaseID:	WBGene00013970	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	65/327 - (19%)
Similarity:	100/327 - (30%)	Gaps:	130/327 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 YNSLKETAPKYSLSLPKKPQLRVSPEEKN----RRRRERIQAKPLNYVCDKCGHTFRQRSQLQMH 342
            ||.|...:.:...::.....|:|.|..|:    ..|.:..:||.:.|.|..||..|....:|..|
Worm   286 YNLLTARSAEDCSTISTPGPLKVFPRSKDDMTFAPRDDSSRAKQMQYPCTLCGQAFAVHDRLAKH 350

  Fly   343 LLRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRHRHERDVHGAG 407
            :                                                  :||||.
Worm   351 I--------------------------------------------------ASRHRQ-------- 357

  Fly   408 NRIRTRVKSKEEGSSRHYCTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQA 472
                 |..:.::.|..|.|..|:||::....|..||..|.|::|:.|..|...|:
Worm   358 -----RSCTLDDASKVHKCNMCSKSFSRSDMLTRHMRLHTGAKPYSCPTCNQVFS---------- 407

  Fly   473 LHDKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICDVHYRHRYNLNKHKNTDLHRDN--- 534
                   |.|          .|:.|...|||..|:.|.:|:.....|..:::|..|....|:
Worm   408 -------RSD----------HLSTHLRTHTGEKPYACPMCNYSASRRDMISRHMRTHSLTDDSSI 455

  Fly   535 ----MQKAIK-----------------EEVNGLQQAFKDI---------DKEMDFES---QTPMQ 566
                .|.:|:                 |..:||..|||.|         .....|:|   .||..
Worm   456 STPISQLSIRSATTSPLPPKIGSTATVEIGSGLLSAFKPILSASSSNLLSVSSPFQSLSLSTPPS 520

  Fly   567 PN 568
            |:
Worm   521 PS 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871
		COG5048	<323..528	CDD:227381	39/204 (19%)
		zf-C2H2	324..346	CDD:278523	7/21 (33%)
		C2H2 Zn finger	326..346	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..375	CDD:275368	0/20 (0%)
		C2H2 Zn finger	383..401	CDD:275368	4/17 (24%)
		C2H2 Zn finger	426..446	CDD:275368	7/19 (37%)
		C2H2 Zn finger	454..474	CDD:275368	3/19 (16%)
		C2H2 Zn finger	481..501	CDD:275368	3/19 (16%)
		C2H2 Zn finger	509..528	CDD:275368	4/18 (22%)
klu-1	NP_493611.2	C2H2 Zn finger	334..354	CDD:275368	6/69 (9%)
		zf-C2H2	369..391	CDD:278523	8/21 (38%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		zf-H2C2_2	383..408	CDD:290200	9/41 (22%)
		COG5048	395..>448	CDD:227381	17/79 (22%)
		C2H2 Zn finger	399..419	CDD:275368	7/46 (15%)
		zf-H2C2_2	411..436	CDD:290200	8/24 (33%)
		C2H2 Zn finger	427..447	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910