DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17803 and Y53H1A.2

DIOPT Version :9

Sequence 1:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001122547.1	Gene:	Y53H1A.2 / 173016	WormBaseID:	WBGene00013178	Length:	214	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	42/184 - (22%)
Similarity:	76/184 - (41%)	Gaps:	38/184 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   323 NYVCDKCG----HTFRQRSQLQMHLLRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPC 383
            ||..|:.|    .|.|       ::....:...:|.      .||..::|:......|.::..|.
Worm    37 NYTSDEDGPKVLTTMR-------NMFAEQKTDEYEL------VYDNNSQNVPQNCSPKNQYSPPQ 88

  Fly   384 NHCNESFANASSRHRHERDVHGAGNRIRTRV---KSK-----------EEGSS--RHYCTQCTKS 432
            :.....::|.|  |.|.|:...:...:..||   ||:           |:|.|  :|.|.:|.|.
Worm    89 SVQQAHYSNLS--HFHPRNPEFSQEIVENRVISPKSEHPEEIEDHEDDEDGQSEMKHNCPECPKK 151

  Fly   433 YTSKKGLVLHMNFHNGSRPFQCKICQMKFADPSAMKRHQALH---DKFPIRCDI 483
            |||::.|..|:..|.....::|:.|...:..|.:::||....   |:||.:.::
Worm   152 YTSERRLKHHIVVHRNPDAYKCQKCGYCYQSPDSLRRHWKKTPNCDEFPPKINV 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871
		COG5048	<323..528	CDD:227381	42/184 (23%)
		zf-C2H2	324..346	CDD:278523	5/25 (20%)
		C2H2 Zn finger	326..346	CDD:275368	4/23 (17%)
		C2H2 Zn finger	354..375	CDD:275368	3/20 (15%)
		C2H2 Zn finger	383..401	CDD:275368	4/17 (24%)
		C2H2 Zn finger	426..446	CDD:275368	8/19 (42%)
		C2H2 Zn finger	454..474	CDD:275368	5/19 (26%)
		C2H2 Zn finger	481..501	CDD:275368	0/3 (0%)
		C2H2 Zn finger	509..528	CDD:275368
Y53H1A.2	NP_001122547.1	C2H2 Zn finger	145..165	CDD:275368	8/19 (42%)
Y53H1A.2	NP_001122547.1	C2H2 Zn finger	173..189	CDD:275368	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910