DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7379 and PHO23

DIOPT Version :9

Sequence 1:	NP_650656.1	Gene:	CG7379 / 42140	FlyBaseID:	FBgn0038546	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_014302.3	Gene:	PHO23 / 855626	SGDID:	S000005041	Length:	330	Species:	Saccharomyces cerevisiae

Alignment Length:	406	Identity:	89/406 - (21%)
Similarity:	156/406 - (38%)	Gaps:	107/406 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VDNYIDSVENLPDDVQRQLSRIRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSR---SISRM 79
            :::..|.:|..|....|.|:.:.:||.:....:.:::...|.:|....:.|...:.|   :|:::
Yeast    11 LNDITDVLEEFPLATSRYLTLLHEIDAKCVHSMPNLNERIDKFLKKDFNKDHQTQVRLLNNINKI 75

  Fly    80 HQSLIQAQELGDEKMQIVNHMQEIIDGKLRQLDTDQQNLDLKEDRDRYALLD-DGTPSK------ 137
            ::.|:.:.|   |||.:.:.|.:.:|....:|:...:......:..|...|. |..|:.
Yeast    76 YEELMPSLE---EKMHVSSIMLDNLDRLTSRLELAYEVAIKNTEIPRGLRLGVDNHPAMHLHHEL 137

  Fly   138 LQRLQSPMREQGNQAGTGNGGLNGNGLLSAKDLYALGG-------YAGGVVPGSNAMTSGNGGGS 195
            :::::|....:.:||           |.|.....|:..       |:.......::....|.|||
Yeast   138 MEKIESKSNSKSSQA-----------LKSESRREAMAANRRQGEHYSASTHQQDDSKNDANYGGS 191

  Fly   196 TPNSERSSHVSNGGNSGSNGNASGGGGGELQRTGSKRSRRRNESVVNNGSSLEMGGNESNSANEA 260
              ..|...|..|..||....||:                                 |.:|:..|.
Yeast   192 --RHESQDHTGNNTNSRKRANAA---------------------------------NTNNADPET 221

  Fly   261 SGSGGGSGERKSSLGGASGAGQGRKASLQSASGSLASGSAATSSGAAGGGGAS-GAGVVGGNNSG 324
            .       :||            |:.:..:.|.|..|.:.|.::|..|...|| |...||.:|:.
Yeast   222 K-------KRK------------RRVATTAVSPSTISTATAVNNGRIGTSTASRGVSSVGNSNNS 267

  Fly   325 KKKKRKVRGSGASNANASTREETPPPETIDPDEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCV 389
            :..:                     |:|.|..||.||.|||:::|||:.||...|.:||||..|:
Yeast   268 RISR---------------------PKTNDYGEPLYCYCNQVAYGEMVGCDGADCELEWFHLPCI 311

  Fly   390 SLVLKPKGKWFCPNCR 405
            .|...|||||:|.:|:
Yeast   312 GLETLPKGKWYCDDCK 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:289749	20/100 (20%)
CG7379	NP_650656.1	PHD_ING1_2	360..404	CDD:277059	23/43 (53%)
PHO23	NP_014302.3	TNG2	5..330	CDD:227367	89/406 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1604
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	1	1.000	-	-		otm46516
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
TreeFam	1	0.960	-	-
	9	8.900