Protein Alignment CG7379 and Ing3

DIOPT Version :10

• Sequence 1: NP_650656.1
• Gene: CG7379 / 42140
• FlyBaseID: FBgn0038546
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_076115.3
• Gene: Ing3 / 71777
• MGIID: 1919027
• Length: 421
• Species: Mus musculus
• Alignment Length: 463
• Identity: 116/463 - (25%)
• Similarity: 188/463 - (40%)
• Gaps: 117/463 - (25%)

  Fly    17 YVDNYIDSVENLPDDVQRQLSRIRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQ 81
            |:::|::.:|.||.|::.:.:.:|::|:|.:..:..::.....:...........|...::.:.:
Mouse     3 YLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKK 67

  Fly    82 SLIQAQELGDEKMQIVNHMQEIIDGKLRQLD---------TDQQNLDLKEDRDRYAL-LD----- 131
            ...:|.|..|||:|:.|.:.:::|..||:||         .:..|..:.|..:|.:| ||
Mouse    68 DYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQP 132

  Fly   132 --------------------------DGTPSKLQRLQSPMREQGNQAGTGN--GGLNGNGLLSAK 168
                                      |..|.|..:.::.:....:.|...|  |..|.|...|..
Mouse   133 VNNHHAHSHTPVEKRKYNPTSHHAAADHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCN 197

  Fly   169 DLYALGGYAGGVVPGSNAMTSGNGGGSTPNSERSSHVSNGGNSGSNGNASGGGGGELQRTGSKRS 233
            :.|.        |..|..:.|.|.|.          :|:|..:|:...|:...   :|.|...:.
Mouse   198 NAYN--------VNSSQPLASYNIGS----------LSSGAGAGAITMAAAQA---VQATAQMKE 241

  Fly   234 RRRN-------ESVVNNGSSLEMGGNESNSANEASGSGGGSG------ERKSSLGGASGAGQGRK 285
            .||.       |:..||...|   |.|.:...|.:|....|.      :..||  .|:.:..|||
Mouse   242 GRRTSSLKASYEAFKNNDFQL---GKEFSIPRETAGYSSSSALMTTLTQNASS--SATDSRSGRK 301

  Fly   286 ASLQSASGSLASGSAATSSGAAGGGGASGAGVVGGNNSGKKKKRKVRGSGASNANASTREETPPP 350
            :...:.|.|..|.|:::||.::.....|.:..|                    ....:::.|..|
Mouse   302 SKNNTKSSSQQSSSSSSSSSSSSLSLCSSSSTV--------------------VQEVSQQATVVP 346

  Fly   351 E---------TIDPDEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKPKGKWFCPNC-- 404
            |         |.||:||.||:|||:|:|||:.|||..|||||||:.||.|...||||||||.|
Mouse   347 ESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQCTA 411

  Fly   405 ----RGER 408
                ||.|
Mouse   412 AMKRRGSR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:463768	22/107 (21%)
		PHD_ING1_2	360..404	CDD:277059	30/43 (70%)
Ing3	NP_076115.3	ING	3..102	CDD:463768	22/98 (22%)
		TNG2	4..413	CDD:227367	112/454 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..163		1/33 (3%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..323		12/38 (32%)
		PHD_ING3	365..409	CDD:277060	30/43 (70%)