Protein Alignment CG7379 and ING4

DIOPT Version :9

• Sequence 1: NP_650656.1
• Gene: CG7379 / 42140
• FlyBaseID: FBgn0038546
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_001121054.1
• Gene: ING4 / 51147
• HGNCID: 19423
• Length: 249
• Species: Homo sapiens
• Alignment Length: 396
• Identity: 91/396 - (22%)
• Similarity: 144/396 - (36%)
• Gaps: 159/396 - (40%)

  Fly    17 YVDNYIDSVENLPDDVQRQLSRIRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQ 81
            |:::|:||:||||.::||....:||:|.:...|..::|.....|:|...|..:..:...:.::.:
Human     6 YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQE 70

  Fly    82 SLIQAQELGDEKMQIVNHMQEIIDGKLRQLDTDQQNLDLKEDRDRYALLDDGTPSKLQRLQSPMR 146
            :..:.:|.||:|:|:.....|::|..:|:||||                       |.|.::.::
Human    71 AYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTD-----------------------LARFEADLK 112

  Fly   147 EQGNQAGTGNGGLNGNGLLSAKDLYALGGYAGGVVPGSNAMTSGNGGGSTPNSERSSHVSNGGNS 211
            |:..::                                                     |:..:|
Human   113 EKQIES-----------------------------------------------------SDYDSS 124

  Fly   212 GSNGNASGGGGGELQRTGSKRSRRRNESVVNNGSSLEMGGNESNSANEASGSGGGSGERKSSLGG 276
            .|.|...|       ||..::...|..|            ...||..||.
Human   125 SSKGKKKG-------RTQKEKKAARARS------------KGKNSDEEAP--------------- 155

  Fly   277 ASGAGQGRKASLQSASGSLASGSAATSSGAAGGGGASGAGVVGGNNSGKKKKRKVRGSGASNANA 341
                                                         .:.:||.:.||.|......:
Human   156 ---------------------------------------------KTAQKKLKLVRTSPEYGMPS 175

  Fly   342 STREETPPPET----IDPDEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKPKGKWFCP 402
            .|.....|.:.    :||:|||||:|:|:|:||||.|||..|.||||||:||.|..||:||||||
Human   176 VTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240

  Fly   403 NCRGER 408
            .|..||
Human   241 RCSQER 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:289749	30/98 (31%)
		PHD_ING1_2	360..404	CDD:277059	30/43 (70%)
ING4	NP_001121054.1	TNG2	7..245	CDD:227367	88/392 (22%)
		ING_ING4	11..104	CDD:341095	28/115 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	115..164		15/180 (8%)
		Bipartite nuclear localization signal	127..148		6/39 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141964
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.780