Protein Alignment CG7379 and ING2

DIOPT Version :10

• Sequence 1: NP_650656.1
• Gene: CG7379 / 42140
• FlyBaseID: FBgn0038546
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_001555.1
• Gene: ING2 / 3622
• HGNCID: 6063
• Length: 280
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 109/419 - (26%)
• Similarity: 166/419 - (39%)
• Gaps: 168/419 - (40%)

  Fly    17 YVDNYIDSVENLPDDVQRQLSRIRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQ 81
            ||.:|::.||:||.|:||.:|.:|::|.:|:..::::|..|:.|   :...|..::.|....:.:
Human    27 YVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKY---KKEDDLNQKKRLQQLLQR 88

  Fly    82 SLIQAQELGDEKMQIVNHMQEIIDGKLRQLDTDQQNLDLKEDRDR---YALLDDGTPSKLQRLQS 143
            :||.:|||||||:|||..|.|:::.:.||::...|......:.:|   .|.:|...|.:..|  .
Human    89 ALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSR--R 151

  Fly   144 PMREQGNQAGTGNGGLNGNGLLSAKDLYALGGYAGGVVPGSNAMTSGNGGGSTPNSERSSHVSNG 208
            |.|::.::               ::||                                .|::||
Human   152 PRRQRTSE---------------SRDL--------------------------------CHMANG 169

  Fly   209 GNSGSNGNASGGGGGELQRTGSKRSRRRNESVVNNGSSLEMGGNESNSANEASGSGGGSGERKSS 273
            .....:           |....|:|:
Human   170 IEDCDD-----------QPPKEKKSK--------------------------------------- 184

  Fly   274 LGGASGAGQGRKASLQSASGSLASGSAATSSGAAGGGGASGAGVVGGNNSGKKKKRKVRGSGASN 338
                                                             |.|||||       |.
Human   185 -------------------------------------------------SAKKKKR-------SK 193

  Fly   339 ANASTREETPPPETIDPDEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKPKGKWFCPN 403
            |. ..||.:|....|||:|||||:|||:|:||||.|||:.|||||||||||||..||||||:||.
Human   194 AK-QEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPK 257

  Fly   404 CRGERPNVMKPKAQFLKELERYNKEKEEK 432
            |||:....|.      |..|:..|::..:
Human   258 CRGDNEKTMD------KSTEKTKKDRRSR 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:463768	35/98 (36%)
		PHD_ING1_2	360..404	CDD:277059	34/43 (79%)
ING2	NP_001555.1	ING_ING2	32..119	CDD:341094	32/89 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..204		27/237 (11%)
		PHD_ING2	213..261	CDD:277153	37/47 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		7/27 (26%)
		PBR. /evidence=ECO:0000269|PubMed:16728974	264..280		4/21 (19%)