Protein Alignment CG7379 and ING1

DIOPT Version :9

• Sequence 1: NP_650656.1
• Gene: CG7379 / 42140
• FlyBaseID: FBgn0038546
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_005528.4
• Gene: ING1 / 3621
• HGNCID: 6062
• Length: 422
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 109/384 - (28%)
• Similarity: 156/384 - (40%)
• Gaps: 152/384 - (39%)

  Fly    46 YRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQSLIQAQELGDEKMQIVNHMQEIIDGKLRQ 110
            ::.:::::|..|:.:   ....|..::.|.:..:.::||::|||||||:|||:.|.|:::.:.||
Human   187 WKQILKELDECYERF---SRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQ 248

  Fly   111 LDTDQQNLDLKEDRDRYALLDDGTPSKLQRLQSPMREQGNQAGTGNGGLNGNGLLSAKDLYALGG 175
            :|:   :::|.|                     ..:|.|:.||
Human   249 VDS---HVELFE---------------------AQQELGDTAG---------------------- 267

  Fly   176 YAGGVVPGSNAMTSGNGGGSTPNSERSSHVSNGGNSGSNGNASGGGGGELQRTGSKRSRRRNESV 240
                        .||..|...|..|.::                    :..:..||||||:.
Human   268 ------------NSGKAGADRPKGEAAA--------------------QADKPNSKRSRRQR--- 297

  Fly   241 VNNGSSLEMGGNESNSANEASGSGGGSGERKSSLGGASGAGQGRKASLQSASGSLASGSAATSSG 305
                       |..|..|.:|......        ||||..:.:||
Human   298 -----------NNENRENASSNHDHDD--------GASGTPKEKKA------------------- 324

  Fly   306 AAGGGGASGAGVVGGNNSGKKKKRKVRGSGASNANASTREETPPPETIDPDEPTYCVCNQISFGE 370
                            .:.|||||       |.|.|. ||.:|....|||:|||||:|||:|:||
Human   325 ----------------KTSKKKKR-------SKAKAE-REASPADLPIDPNEPTYCLCNQVSYGE 365

  Fly   371 MILCDNDLCPIEWFHFSCVSLVLKPKGKWFCPNCRGERPNVMKPKAQFLKELERYNKEK 429
            ||.||||.|||||||||||.|..||||||:||.||||....|.      |.||:..||:
Human   366 MIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMD------KALEKSKKER 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:289749	21/69 (30%)
		PHD_ING1_2	360..404	CDD:277059	34/43 (79%)
ING1	NP_005528.4	ING	<189..254	CDD:289749	21/70 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..349		36/206 (17%)
		PHD_ING1_2	355..399	CDD:277059	34/43 (79%)
		PBR. /evidence=ECO:0000250|UniProtKB:Q9H160	405..422		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40119
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3742
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109185
Panther	1	1.100	-	-	LDO	PTHR10333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.790