DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7379 and ing4

DIOPT Version :9

Sequence 1:	NP_650656.1	Gene:	CG7379 / 42140	FlyBaseID:	FBgn0038546	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001018304.1	Gene:	ing4 / 322113	ZFINID:	ZDB-GENE-050522-47	Length:	250	Species:	Danio rerio

Alignment Length:	392	Identity:	91/392 - (23%)
Similarity:	151/392 - (38%)	Gaps:	150/392 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YVDNYIDSVENLPDDVQRQLSRIRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQ 81
            |:::|:||:||||.::||....:||:|.:...|...:|.....|.:...:..:.::...:.::.|
Zfish     6 YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKGQIDSLAREYTANARTLSSEQKLSLLRQIQQ 70

  Fly    82 SLIQAQELGDEKMQIVNHMQEIIDGKLRQLDTDQQNLDLKEDRDRYALLDDGTPSKLQRLQSPMR 146
            |..:.:|.||:|:|:.....|::|..:|:||||                       |.|.::.::
Zfish    71 SYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTD-----------------------LARFEADLK 112

  Fly   147 EQGNQAGTGNGGLNGNGLLSAKDLYALGGYAGGVVPGSNAMTSGNGGGSTPNSERSSHVSNGGNS 211
            |:..::                                                     ::..::
Zfish   113 EKQIES-----------------------------------------------------TDYDST 124

  Fly   212 GSNGNASGGGGGELQRTGSKRSRRRNESVVNNGSSLEMGGNESNSANEASGSGGGSGERKSSLGG 276
            .|.||.|...|.:.:.....||:.:                  ||.::.|..   ||::|..|
Zfish   125 SSKGNKSDIRGPKKKEVNRARSKVK------------------NSDDDCSSK---SGQKKVKL-- 166

  Fly   277 ASGAGQGRKASLQSASGSLASGSAATSSGAAGGGGASGAGVVGGNNSGKKKKRKVRGSGASNANA 341
                                :.|...|:.|...|                           |.:.
Zfish   167 --------------------TQSTEFSTPAVNFG---------------------------NVHP 184

  Fly   342 STREETPPPETIDPDEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKPKGKWFCPNCRG 406
            |...:.|    :||:|||||:|:|:|:||||.|||..|.||||||:||.|..||:|||:||.|..
Zfish   185 SDVLDMP----VDPNEPTYCLCHQVSYGEMIGCDNTDCSIEWFHFACVGLTTKPRGKWYCPRCSQ 245

  Fly   407 ER 408
            ||
Zfish   246 ER 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:289749	30/98 (31%)
CG7379	NP_650656.1	PHD_ING1_2	360..404	CDD:277059	29/43 (67%)
ing4	NP_001018304.1	ING	6..105	CDD:289749	30/121 (25%)
		TNG2	7..246	CDD:227367	88/388 (23%)
		PHD_ING4	198..245	CDD:277154	31/46 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574875
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.780