DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7379 and png2

DIOPT Version :9

Sequence 1:	NP_650656.1	Gene:	CG7379 / 42140	FlyBaseID:	FBgn0038546	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001342766.1	Gene:	png2 / 2539953	PomBaseID:	SPBC1709.11c	Length:	305	Species:	Schizosaccharomyces pombe

Alignment Length:	399	Identity:	88/399 - (22%)
Similarity:	146/399 - (36%)	Gaps:	128/399 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VDNYIDSVENLPDDVQRQLSRIRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQS 82
            ::::.|::.::|:.|..:.:.:::||.|.|.:.::|.....:.|..:.:.:.....| ..|:.::
pombe    12 LNDFTDAIVSVPESVCGKFTSLKEIDAQVRDIRQNVIQEIGVVLKNEKNDELSGEER-CERLQKT 75

  Fly    83 LIQAQELGDEKM----QIVNHMQEIIDGKLRQLDTDQQNLDLKEDRDRYALLDDGTPSKLQRLQS 143
            |.:.....|.|:    ..:|:::..||    :||...:.::|:            .|.:| ||..
pombe    76 LKEILPYSDSKICLATDAMNNIKSCID----RLDAGFEYVELE------------IPQQL-RLGY 123

  Fly   144 PMREQGNQAGTGNGGLNGNGLLSAKDLYALGGYAGGVVPGSNAMTSGNGGGSTPNSERSSHVSNG 208
            |                        |..||..|...|.|              ..|||
pombe   124 P------------------------DDRALMNYHSTVTP--------------QTSER------- 143

  Fly   209 GNSGSNGNASGGGGGELQRTGSKRSRRRNESVVNNGSSLEMGGNESNSANEASGSGGGSGERKSS 273
                                  :|..||::   ||..|      :..|:.|.|.|.....:..|.
pombe   144 ----------------------RRETRRHQ---NNQHS------QQYSSQERSSSYNNFEDASSP 177

  Fly   274 LGGASGAGQGRKASL--QSASGSLASGSAATSSGAAGGGGASGAGVVGGNNSGKKKKRKVRGSGA 336
            ........:.||.::  :|:|..|:|...|..|                     .::|.||.| .
pombe   178 QSSYHTPTKRRKNAVPRKSSSPPLSSTKHAPQS---------------------TERRPVRRS-E 220

  Fly   337 SNANASTREETPPPETIDPD------EPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKP 395
            |....:..|.....:|:|..      |..||.|.|:|:|:||.|||:.|..||||..||.||..|
pombe   221 SRLKQTNGEPLVKHDTLDSSDISREGEQLYCYCQQVSYGQMIGCDNENCKREWFHLPCVGLVEPP 285

  Fly   396 KGKWFCPNC 404
            ||.|:|..|
pombe   286 KGIWYCKEC 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7379	NP_650656.1	ING	17..116	CDD:289749	19/101 (19%)
CG7379	NP_650656.1	PHD_ING1_2	360..404	CDD:277059	25/43 (58%)
png2	NP_001342766.1	TNG2	6..298	CDD:227367	88/399 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	83	1.000	Domainoid score	I2247
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	1	1.000	-	-		mtm9268
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
TreeFam	1	0.960	-	-
	9	8.900