Protein Alignment TyrR and adra1ab

DIOPT Version :9

• Sequence 1: NP_001287381.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_021334987.1
• Gene: adra1ab / 557259
• ZFINID: ZDB-GENE-060503-384
• Length: 431
• Species: Danio rerio
• Alignment Length: 489
• Identity: 134/489 - (27%)
• Similarity: 193/489 - (39%)
• Gaps: 176/489 - (35%)

  Fly   117 IILIAVFATFIVVTVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLIGS 181
            ::|..|...|::..|:||.||||::...|.||::|:.|:.:||:||||:...|:|.:.....:|.
Zfish    37 LVLGLVLVLFLIFGVMGNILVILSVACHRNLRSVTHYFIGNLAIADLLLSSVVLPFSAVSEALGR 101

  Fly   182 WQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIVWLLAL 246
            |..|..||:.|.:||||.|||||||||.|||||.:||:.||.|......:| |:..:..:|.|:.
Zfish   102 WVFGRHLCNAWTALDVLCCTASILSLCVISVDRCMAVSYPLQYPSFATGRR-AMTAVAALWALSA 165

  Fly   247 AITCPPMLGWYEPGRRDLRECRYNQNEGYVIFSAMGSFFIPMAVMIYVYARISCVIASRHDNMTD 311
            ||:..|:.||.||...|...||.|::.||.||||..||::|:||::.:|.|:  .:.:||
Zfish   166 AISVGPLFGWREPMPEDESVCRVNEDPGYAIFSAACSFYVPLAVILAMYCRV--YVVARH----- 223

  Fly   312 ISVHNKKFKRYTAADVENELSEQEQHSSVGQRQRQATSRTFSNQTIAKELQDMMLSDSDNCAAMG 376
                  |.:..:.:...|.||||      |...|
Zfish   224 ------KTRAMSKSRETNGLSEQ------GMTLR------------------------------- 245

  Fly   377 AGGAGGGGGGASSATGGTHCQSLLALPSGGVGGSMGCAKNGCYELTRPSSLKRASTASTTITTMT 441
                             .||:.               |:|.    ||
Zfish   246 -----------------IHCRK---------------AQND----TR------------------ 256

  Fly   442 SGMGPGSSLLDAQWQSQPPGQTGQVQTHSLSQPPRTHSFRHSHGERDRERLRSHHHHPHYHHQAG 506
                                                        :.|..||:
Zfish   257 --------------------------------------------KEDAMRLK------------- 264

  Fly   507 VTTTSTSGNTSANTNSKSLSNRITSLKKENKTTQTLSIVVGGFIACWLPFFINYLITPFLAEHQA 571
                          ||.....|:....:|.|..:||.||||.|:.||||||:...|:.....|:.
Zfish   265 --------------NSHFAFMRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVLPISSIFPSHRP 315

  Fly   572 SQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAF 605
            ...:.|...|||:|||.:||.||..:|.:|:.||
Zfish   316 PDAVFKITFWLGYFNSCLNPIIYPCFSQEFKKAF 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_001287381.1	7tm_4	127..>249	CDD:304433	54/121 (45%)
		7tm_1	133..>298	CDD:278431	75/164 (46%)
adra1ab	XP_021334987.1	7tm_GPCRs	48..349	CDD:333717	129/476 (27%)
		TM helix 2	72..94	CDD:320095	9/21 (43%)
		TM helix 3	110..132	CDD:320095	15/21 (71%)
		TM helix 4	155..171	CDD:320095	4/15 (27%)
		TM helix 5	192..215	CDD:320095	11/22 (50%)
		TM helix 6	280..305	CDD:320095	14/24 (58%)
		TM helix 7	317..342	CDD:320095	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010