Protein Alignment TyrR and mAChR-B

DIOPT Version :9

• Sequence 1: NP_001287381.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Alignment Length: 947
• Identity: 174/947 - (18%)
• Similarity: 274/947 - (28%)
• Gaps: 445/947 - (46%)

  Fly    65 GGGYPSGPNGTDAVALTEPGPTAPVTTFNYYNESAAAAEWAHFYDLVLSWQGIILIAVFATFIVV 129
            ||...|| :.:|:..|   ||..|....                     ||.|::....|..|::
  Fly   107 GGSTMSG-SSSDSEIL---GPVLPPFAL---------------------WQTILIAICLAICIIL 146

  Fly   130 TVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLIGSWQLGWVLCDIWIS 194
            ||.||.||:||.:..|.:|..:|.|:.|||..|:|:|...||......|.|.|.||.:|||:|:|
  Fly   147 TVGGNILVLLAFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLS 211

  Fly   195 LDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIVWLLALAITCPPMLGW-YE 258
            :|..:|..|..::..|::|||.:|.....| |..|::...:.|:.|.|::...:....:.|| :.
  Fly   212 VDYTVCLVSQYTVLLITIDRYCSVKIAAKY-RSWRTRTRVIYMVTITWIIPALLFFISIFGWEHF 275

  Fly   259 PGRRDL--RECRYNQNEGYVIFSAM--GSFFIPMAVMIYVYA------------------RISCV 301
            .|:|||  .:|.....:..:..:|:  |.::..:.|:..:||                  ::..:
  Fly   276 TGKRDLLPGQCAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAGIYKTAYDMQKRSEAKQRKMQSM 340

  Fly   302 IASRHDNMTDISVH--------------------------------------------------- 315
            :|.....|:.::.|
  Fly   341 VALSAGAMSGMAGHAAGIGVIEEKILKTKVELAGDQTDLDSACTTVIKRLSGSGQANPLAVATEE 405

  Fly   316 ----NKKFKRYTAADVENELSEQE-------------------QHSSVGQRQRQATSRTFSNQTI 357
                ..:.:|.:||.::.|..::|                   :.|||.|.|:..|.:..:|
  Fly   406 VEKMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNN--- 467

  Fly   358 AKELQDMMLSDSDNCAAMGAGGA----GGGGGGASSATGG------------------------- 393
                   |...|......||..|    .|.|....|.|..
  Fly   468 -------MRKRSSIGLVFGAQAALLATRGKGNLQKSTTNSKSIEAMHQYHHHQQHHHNQSPLQRA 525

  Fly   394 ------------------------------------THCQSL----------------------- 399
                                                |.|.:|
  Fly   526 QSKEEMRSLHHHQNQQQPHHQHHQNQPNPPLDRPKRTSCSTLSQIAEHDRLVDLSAPPTLLNTSD 590

  Fly   400 ---------LALPSGGV------------------------------GGSMGCAKNG-CYELTRP 424
                     :.:||..|                              |.|.|.::.. .|:|...
  Fly   591 PLSPVDLAPIEVPSDQVHQGLVQTILPPPDAFQCPTPLSDDYSDRPFGNSSGNSELALTYDLMTN 655

  Fly   425 SSLK-----RASTASTTITTMTS------GMGP-----------------GSSLLDAQWQSQPPG 461
            |.|:     .|..||.|..:.||      |..|                 ..||.....|:|.|.
  Fly   656 SELRYMDESSAMLASVTANSTTSPNDSVQGKPPVLPPPPPARRNPPKSNLNQSLSQTPSQNQSPS 720

  Fly   462 QT---------GQVQTHSL---------------------------------------------- 471
            |:         .|.|:.|:
  Fly   721 QSLSLNLNPNHNQSQSQSIEEAVAIEKRLLVSYTGIEDFAKVRRESCIEAICLLDVPGKLAADCP 785

  Fly   472 ----SQP---------------------------PRTHSFRHSHG-------ERDRERLRSHHHH 498
                |.|                           |:|.:.:.:.|       ||..||..|..:.
  Fly   786 HRRASSPMETSSKDAILYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTPPVPLERIEERETSDSNT 850

  Fly   499 PHYHHQAGVTTTST------------------SGNTSANTNSKSLSNRITSLKK----------- 534
            ......:| ||:||                  :|:..||...|||:....|.|:
  Fly   851 NKMPSTSG-TTSSTGGVGGGGEQDGVGATKKNAGDDDANREEKSLAASRNSSKRAFIHSIGKHFK 914

  Fly   535 -------------------EN---KTTQTLSIVVGGFIACWLPFFINYLI------TPFLAEHQA 571
                               ||   |..:|:|.::|.|:|||.|:.:..|:      .|.:.||
  Fly   915 SKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALVEGFCRHPPCINEH-- 977

  Fly   572 SQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAFWRL 608
               |.....:|.:.||.:|||.||..:..|:..|.|:
  Fly   978 ---LYMFSYFLCYANSPMNPFCYALANQQFKKTFTRI 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_001287381.1	7tm_4	127..>249	CDD:304433	45/121 (37%)
		7tm_1	133..>298	CDD:278431	54/187 (29%)
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	54/191 (28%)
		7tm_4	150..>336	CDD:304433	54/186 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460693
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840