Protein Alignment TyrR and adra2a

DIOPT Version :9

• Sequence 1: NP_001287381.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_997520.3
• Gene: adra2a / 266750
• ZFINID: ZDB-GENE-021010-1
• Length: 388
• Species: Danio rerio
• Alignment Length: 521
• Identity: 146/521 - (28%)
• Similarity: 224/521 - (42%)
• Gaps: 145/521 - (27%)

  Fly    93 NYYNESAAAAEWAHFYDLVLSWQGIILIAVFATFIVVTVIGNTLVILAILTTRRLRTITNCFVMS 157
            |..|.:.|..|:.....|.||      :|| ...|::.:.||.|||:|:.|:|.||...|.|::|
Zfish     6 NATNGTNATKEYTLLVALPLS------VAV-GLLILLIIFGNVLVIIAVFTSRALRAPQNLFLVS 63

  Fly   158 LAVADLLVGIFVMPPAVAVHLIGSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPL 222
            ||.||:||...|||.::|..|:|.|..|.|.|:|:::||||.|||||..|||||:|||.::|:.:
Zfish    64 LASADILVATLVMPFSLANELMGMWTFGGVWCEIYLALDVLFCTASITHLCAISLDRYWSITQAI 128

  Fly   223 TYSRKRRSKRLALIMILIVWLLALAITCPPMLGWYEPGRRDLRECRYNQNEGYVIFSAMGSFFIP 287
            .|:.||..:|:..| |.|||::|..|:|||:: ..:....|:  |..|:.:.|::.|.:||||:|
Zfish   129 EYNLKRTPQRIKRI-IFIVWIIAAVISCPPLI-TMKKSEGDI--CDINKEKWYIVSSCIGSFFLP 189

  Fly   288 MAVMIYVYARISCVIASRHDNMTDISVHNKKFKRYTAADVENELSEQEQHSSVGQRQRQATSRTF 352
            ..:|:.||.||..:.              ||..|....|        .:.:.||:::.....:
Zfish   190 CIIMVLVYIRIYQIA--------------KKRTRAPPGD--------HRKNEVGKKENDPHEK-- 230

  Fly   353 SNQTIAKELQDMMLSDSDNCAAMGAGGAGGGGGGASSATGGTHCQSLLALPSGGVGGSMGCAKNG 417
                 ...:|:....|.|...                                  |..|..:.:.
Zfish   231 -----LNGIQNAEPDDKDEIN----------------------------------GVDMEESSSS 256

  Fly   418 CYELTRPSSLKRASTASTTITTMTSGMGPGSSLLDAQWQSQPPGQTGQVQTHSLSQ-PPRTHSFR 481
            .::::.|.|||:.|:...|                                 .||| .|
Zfish   257 DHKVSNPCSLKKKSSKGKT---------------------------------KLSQIKP------ 282

  Fly   482 HSHGERDRERLRSHHHHPHYHHQAGVTTTSTSGNTSANTNSKSLSNRITSLKKENKTTQTLSIVV 546
               |:.|:                    |.....|.| :..|...||      |.:.|..|::|:
Zfish   283 ---GDGDK--------------------TEACQTTKA-SRWKGRQNR------EKRFTFVLAVVI 317

  Fly   547 GGFIACWLPFFINYLITPFLAEHQASQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAFWRLTCK 611
            |.|:.||.|||..|..|.| .:....:.|.|...|.|:.||::||.||..::.|||.:|.::.|:
Zfish   318 GVFVICWFPFFFTYTFTAF-CDCCVPETLFKFFFWFGYCNSSLNPIIYTIFNNDFRRSFKKILCR 381

  Fly   612 R 612
            |
Zfish   382 R 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_001287381.1	7tm_4	127..>249	CDD:304433	59/121 (49%)
		7tm_1	133..>298	CDD:278431	75/164 (46%)
adra2a	NP_997520.3	7tm_4	31..>165	CDD:304433	63/135 (47%)
		7tm_1	39..364	CDD:278431	128/461 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..291		22/193 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910